Seema Husain
Overview
Explore the profile of Seema Husain including associated specialties, affiliations and a list of published articles.
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18
Citations
319
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Recent Articles
1.
Hoque M, DMello V, Husain S, Soteropoulos P
Methods Mol Biol
. 2024 Nov;
2866:207-227.
PMID: 39546205
Formalin fixed paraffin embedded (FFPE) tissues have long been used for immunohistological analyses. FFPE tissues can be stored at room temperature for several years enabling analyses to be performed later....
2.
Das A, Liu T, Li H, Husain S
mSphere
. 2023 Aug;
8(5):e0027323.
PMID: 37581443
RNA-binding proteins (RBPs) are key players in coordinated post-transcriptional regulation of functionally related genes, defined as RNA regulons. RNA regulons play particularly critical roles in parasitic trypanosomes, which exhibit unregulated...
3.
Korczeniewska O, Husain S, Hoque M, Soteropoulos P, Khan J, Eliav E, et al.
J Pain
. 2023 Jul;
25(1):101-117.
PMID: 37524222
Mechanisms underlying neuropathic pain (NP) are complex with multiple genes, their interactions, environmental and epigenetic factors being implicated. Transcriptional changes in the trigeminal (TG) and dorsal root (DRG) ganglia have...
4.
Ramasamy S, Kolloli A, Kumar R, Husain S, Soteropoulos P, Chang T, et al.
Biomedicines
. 2022 Jun;
10(6).
PMID: 35740365
The Coronavirus disease 2019 (COVID-19) pandemic disproportionately affects immunocompetent and immunocompromised individuals, with the latter group being more vulnerable to severe disease and death. However, the differential pathogenesis of SARS-CoV-2...
5.
Lovey A, Verma S, Kaipilyawar V, Ribeiro-Rodrigues R, Husain S, Palaci M, et al.
Nat Commun
. 2022 Feb;
13(1):884.
PMID: 35173157
Mechanisms underlying variability in transmission of Mycobacterium tuberculosis strains remain undefined. By characterizing high and low transmission strains of M.tuberculosis in mice, we show here that high transmission M.tuberculosis strain...
6.
Li S, De La Cruz J, Hutchens S, Mukhopadhyay S, Criss Z, Aita R, et al.
Mol Cell Biol
. 2020 Nov;
41(1).
PMID: 33139494
Although vitamin D is critical for the function of the intestine, most studies have focused on the duodenum. We show that transgenic expression of the vitamin D receptor (VDR) only...
7.
Safi H, Lingaraju S, Ma S, Husain S, Hoque M, Soteropoulos P, et al.
Antimicrob Agents Chemother
. 2020 Jun;
64(9).
PMID: 32571828
We have identified a previously unknown mechanism of reversible high-level ethambutol (EMB) resistance in that is caused by a reversible frameshift mutation in the gene. A frameshift mutation in produces...
8.
Korczeniewska O, Katzmann Rider G, Gajra S, Narra V, Ramavajla V, Chang Y, et al.
Eur J Pain
. 2020 Feb;
24(5):967-982.
PMID: 32100907
Background: The dorsal root (DRG) and trigeminal (TG) ganglia contain cell bodies of sensory neurons of spinal and trigeminal systems, respectively. They are homologs of each other; however, differences in...
9.
Cao C, Wang Y, Husain S, Soteropoulos P, Xue C
mBio
. 2019 Dec;
10(6).
PMID: 31822582
Echinocandins show fungicidal activity against common invasive mycoses but are ineffective against cryptococcosis. The underlying mechanism for echinocandin resistance in remains poorly understood but has been shown to involve Cdc50,...
10.
Safi H, Gopal P, Lingaraju S, Ma S, Levine C, Dartois V, et al.
Proc Natl Acad Sci U S A
. 2019 Sep;
116(39):19665-19674.
PMID: 31488707
The length and complexity of tuberculosis (TB) therapy, as well as the propensity of to develop drug resistance, are major barriers to global TB control efforts. is known to have...