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David Alland

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Articles 145
Citations 7907
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Recent Articles
1.
Sharma P, Jiang Q, Li S, Ocke E, Tsotetsi K, Sukheja P, et al.
J Med Chem . 2025 Mar; 68(5):5774-5803. PMID: 40035499
A dire need exists for novel drugs to treat infection. In an effort to build on our early efforts targeting the MenG enzyme within the menaquinone biosynthetic pathway, we have...
2.
Chilambi G, Reiss R, Daivaa N, Banada P, De Vos M, Penn-Nicholson A, et al.
Microbiol Spectr . 2025 Jan; 13(3):e0240324. PMID: 39873526
Tongue swabs represent a potential alternative to sputum as a sample type for detecting pulmonary tuberculosis (TB) with molecular diagnostic tests. The methods used to process tongue swabs for testing...
3.
Jaganath D, Nabeta P, Nicol M, Castro R, Wambi P, Zar H, et al.
medRxiv . 2025 Jan; PMID: 39763536
Background: Centrifuge-free processing methods support stool Xpert Ultra testing for childhood tuberculosis (TB), but there are limited data on their accuracy, acceptability and usability. Methods: We conducted a prospective evaluation...
4.
Mandecki W, Chudaev M, Ye W, Wang A, Wilson K, Xu X, et al.
Appl Environ Microbiol . 2024 Dec; 91(1):e0204624. PMID: 39714192
Because of the urgent need for new antibiotics to treat drug-resistant bacterial pathogens, we employed an assay that rapidly screens large quantities of compounds for their ability to interfere with...
5.
Chilambi G, Reiss R, Daivaa N, Banada P, De Vos M, Penn-Nicholson A, et al.
medRxiv . 2024 Jul; PMID: 38947094
Importance: Xpert MTB/RIF Ultra (Xpert Ultra) is approved by the World Health Organization for the diagnosis of tuberculosis (TB). This test is typically performed using sputum specimens obtained from people...
6.
Banik S, Ozay B, Trejo M, Zhu Y, Kanna C, Santellan C, et al.
J Clin Microbiol . 2024 Jun; 62(7):e0052524. PMID: 38888304
Importance: This study has the potential to offer a better solution to healthcare providers at hospitals and long-term care facilities in their ongoing efforts for effective and timely control of...
7.
Xie Y, Eichberg C, Hapeela N, Nakabugo E, Anyango I, Arora K, et al.
Lancet Microbe . 2024 Apr; 5(6):e520-e528. PMID: 38608680
Background: Xpert MTB/RIF Ultra (Ultra) is an automated molecular test for the detection of Mycobacterium tuberculosis in sputum. We compared the sensitivity of Ultra to that of mycobacterial growth indicator...
8.
Banada P, Green R, Streck D, Kurvathi R, Reiss R, Banik S, et al.
Sci Rep . 2023 Dec; 13(1):21927. PMID: 38081834
The continued emergence of vaccine-resistant SARS-CoV-2 variants of concern (VOC) requires specific identification of each VOC as it arises. Here, we report an expanded version of our previously described sloppy...
9.
Esmail H, Coussens A, Thienemann F, Sossen B, Mukasa S, Warwick J, et al.
medRxiv . 2023 Jul; PMID: 37461515
Background: The evolution of tuberculosis (TB) disease during the clinical latency period remains incompletely understood. Methods: 250 HIV-uninfected, adult household contacts of rifampicin-resistant TB with a negative symptom screen underwent...
10.
Nsubuga G, Kennedy S, Rani Y, Hafiz Z, Kim S, Ruhwald M, et al.
J Clin Tuberc Other Mycobact Dis . 2023 Apr; 31:100362. PMID: 37006993
Background: The NOVA Tuberculosis Total Antibody Rapid Test is a commercially available lateral flow serological assay that is intended to be used as an aid in the diagnosis of tuberculosis....