Sebastian Oeck
Overview
Explore the profile of Sebastian Oeck including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
760
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Recent Articles
1.
Janetzko J, Oeck S, Schramm A
Cancers (Basel)
. 2023 Dec;
15(23).
PMID: 38067205
Emerging evidence suggests that lamin functions are not limited to maintaining the structural integrity of the nucleus in eukaryotic cells but that these functions affect many facets of cancer biology....
2.
Oeck S, Tuns A, Schramm A
Methods Mol Biol
. 2023 May;
2649:209-221.
PMID: 37258864
Whole genome and transcriptome analyses represent powerful tools. Despite improvements in sequencing methodology, whole transcriptome analyses are still tedious, especially for methodologies producing long reads. Here, we compare the sequence...
3.
Thumser-Henner C, Oeck S, Kalmbach S, Forster J, Kindl F, Sak A, et al.
Cell Death Dis
. 2022 Jun;
13(6):529.
PMID: 35668077
Radiotherapy is an important modality in lung cancer treatment. Despite advances in treatment planning and dose delivery, patient benefit is still limited by in-field relapse and metastatic recurrence. Simultaneous application...
4.
Malewicz N, Rattray Z, Oeck S, Jung S, Escamilla-Rivera V, Chen Z, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563669
Background: Capsaicin, the hot pepper agent, produces burning followed by desensitization. To treat localized itch or pain with minimal burning, low capsaicin concentrations can be repeatedly applied. We hypothesized that...
5.
Hassiepen C, Soni A, Rudolf I, Boron V, Oeck S, Iliakis G, et al.
Cancers (Basel)
. 2021 Dec;
13(23).
PMID: 34885133
High expression of the receptor tyrosine kinase TrkA/NTRK1 is associated with a favorable outcome in several solid tumors of childhood including neuroblastoma. During development, TrkA/NTRK1 governs migration and differentiation of...
6.
Dorsch M, Kowalczyk M, Planque M, Heilmann G, Urban S, Dujardin P, et al.
Cell Rep
. 2021 Nov;
37(8):110056.
PMID: 34818551
Statins are among the most commonly prescribed drugs, and around every fourth person above the age of 40 is on statin medication. Therefore, it is of utmost clinical importance to...
7.
Funke L, Bracht T, Oeck S, Schork K, Stepath M, Dreesmann S, et al.
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771457
(1) Background: Neuroblastomas (NBs) are the most common extracranial solid tumors of children. The amplification of the Myc-N proto-oncogene (MYCN) is a major driver of NB aggressiveness, while high expression...
8.
Ho C, Tuns A, Schildhaus H, Wiesweg M, Gruner B, Hegedus B, et al.
Eur J Cancer
. 2021 Oct;
159:16-23.
PMID: 34715459
Introduction: Mutant RAS guanosine triphosphate hydrolases (GTPases) are key oncogenic drivers in many cancers. The KRAS variant has recently become targetable by a new drug class specifically locking KRAS in...
9.
Differential immunomodulatory effect of PARP inhibition in BRCA1 deficient and competent tumor cells
Alvarado-Cruz I, Mahmoud M, Khan M, Zhao S, Oeck S, Meas R, et al.
Biochem Pharmacol
. 2020 Dec;
184:114359.
PMID: 33285109
Poly-ADP-ribose polymerase (PARP) inhibitors are active against cells and tumors with defects in homology-directed repair as a result of synthetic lethality. PARP inhibitors (PARPi) have been suggested to act by...
10.
Oeck S, Tuns A, Hurst S, Schramm A
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33019615
Transcriptome analyses allow for linking RNA expression profiles to cellular pathways and phenotypes. Despite improvements in sequencing methodology, whole transcriptome analyses are still tedious, especially for methodologies producing long reads....