Sebastian Fritzwanker
Overview
Explore the profile of Sebastian Fritzwanker including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
231
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Recent Articles
1.
Underwood O, Fritzwanker S, Glenn J, Blum N, Batista-Gondin A, Drube J, et al.
Commun Biol
. 2024 Aug;
7(1):933.
PMID: 39095612
Desensitisation of the mu-opioid receptor (MOR) is proposed to underlie the initiation of opioid analgesic tolerance and previous work has shown that agonist-induced phosphorylation of the MOR C-tail contributes to...
2.
Fritzwanker S, Nagel F, Kliewer A, Stammer V, Schulz S
Commun Biol
. 2023 Apr;
6(1):419.
PMID: 37061609
G protein-coupled receptors (GPCRs) are important signal transducers that are phosphorylated upon activation at intracellular serine and threonine residues. Although antibodies that specifically recognize the phosphorylation state of GPCRs have...
3.
Kaufmann J, Blum N, Nagel F, Schuler A, Drube J, Degenhart C, et al.
Commun Biol
. 2022 Nov;
5(1):1206.
PMID: 36352263
Analysis of agonist-driven phosphorylation of G protein-coupled receptors (GPCRs) can provide valuable insights into the receptor activation state and ligand pharmacology. However, to date, assessment of GPCR phosphorylation using high-throughput...
4.
Fritzwanker S, Mouledous L, Mollereau C, Froment C, Burlet-Schiltz O, Effah F, et al.
Commun Biol
. 2021 Sep;
4(1):1070.
PMID: 34522000
G protein-coupled receptors (GPCRs) are notoriously difficult to detect in native tissues. In an effort to resolve this problem, we have developed a novel mouse model by fusing the hemagglutinin...
5.
Fritzwanker S, Schulz S, Kliewer A
Molecules
. 2021 Aug;
26(15).
PMID: 34361663
Opioid-associated overdoses and deaths due to respiratory depression are a major public health problem in the US and other Western countries. In the past decade, much research effort has been...
6.
Gillis A, Gondin A, Kliewer A, Sanchez J, Lim H, Alamein C, et al.
Sci Signal
. 2020 Apr;
13(625).
PMID: 32234959
Biased agonism at G protein-coupled receptors describes the phenomenon whereby some drugs can activate some downstream signaling activities to the relative exclusion of others. Descriptions of biased agonism focusing on...
7.
Rudeck J, Vogl S, Heinl C, Steinfath M, Fritzwanker S, Kliewer A, et al.
Pharmacol Biochem Behav
. 2020 Feb;
191:172877.
PMID: 32088361
Buprenorphine is a commonly used opioid to treat moderate to severe pain in mice. Although strain differences regarding basal pain sensitivity and the analgesic effect of other opioids have been...
8.
Gunther T, Dasgupta P, Mann A, Miess E, Kliewer A, Fritzwanker S, et al.
Br J Pharmacol
. 2017 Apr;
175(14):2857-2868.
PMID: 28378462
Linked Articles: This article is part of a themed section on Emerging Areas of Opioid Pharmacology. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v175.14/issuetoc.