Rainer K Reinscheid
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Explore the profile of Rainer K Reinscheid including associated specialties, affiliations and a list of published articles.
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64
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1706
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Recent Articles
1.
Blum N, Schaffner A, Drube J, Nagel F, Reinscheid R, Hoffmann C, et al.
Eur J Pharmacol
. 2024 Apr;
973:176587.
PMID: 38642667
Agonist-induced phosphorylation is a crucial step in the activation/deactivation cycle of G protein-coupled receptors (GPCRs), but direct determination of individual phosphorylation events has remained a major challenge. We have recently...
2.
Alexander S, Christopoulos A, Davenport A, Kelly E, Mathie A, Peters J, et al.
Br J Pharmacol
. 2023 Dec;
180 Suppl 2:S23-S144.
PMID: 38123151
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
3.
Kaufmann J, Blum N, Nagel F, Schuler A, Drube J, Degenhart C, et al.
Commun Biol
. 2022 Nov;
5(1):1206.
PMID: 36352263
Analysis of agonist-driven phosphorylation of G protein-coupled receptors (GPCRs) can provide valuable insights into the receptor activation state and ligand pharmacology. However, to date, assessment of GPCR phosphorylation using high-throughput...
4.
Garau C, Liu X, Calo G, Schulz S, Reinscheid R
Neuroscience
. 2022 Jun;
496:83-95.
PMID: 35710064
Evaluation of stimulus salience is critical for any higher organism, as it allows for prioritizing of vital information, preparation of responses, and formation of valuable memory. The paraventricular nucleus of...
5.
Dasgupta P, Mann A, Polgar W, Reinscheid R, Zaveri N, Schulz S
Sci Rep
. 2022 May;
12(1):7154.
PMID: 35504962
Multi-receptor targeting has been proposed as a promising strategy for the development of opioid analgesics with fewer side effects. Cebranopadol and AT-121 are prototypical bifunctional ligands targeting the nociceptin/orphanin FQ...
6.
Alexander S, Christopoulos A, Davenport A, Kelly E, Mathie A, Peters J, et al.
Br J Pharmacol
. 2021 Sep;
178 Suppl 1:S27-S156.
PMID: 34529832
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of...
7.
Fritzwanker S, Mouledous L, Mollereau C, Froment C, Burlet-Schiltz O, Effah F, et al.
Commun Biol
. 2021 Sep;
4(1):1070.
PMID: 34522000
G protein-coupled receptors (GPCRs) are notoriously difficult to detect in native tissues. In an effort to resolve this problem, we have developed a novel mouse model by fusing the hemagglutinin...
8.
Si W, Liu X, Pape H, Reinscheid R
Pharmaceuticals (Basel)
. 2021 Jun;
14(5).
PMID: 34065431
Conflicting reports about the role of neuropeptide S (NPS) in animal models of psychotic-like behavior and inconsistent results from human genetic studies seeking potential associations with schizophrenia prompted us to...
9.
Reinscheid R, Ruzza C
Pharmaceuticals (Basel)
. 2021 Apr;
14(5).
PMID: 33922620
The Neuropeptide S (NPS) system is a rather 'young' transmitter system that was discovered and functionally described less than 20 years ago. This review highlights the progress that has been...
10.
Albanese V, Ruzza C, Marzola E, Bernardi T, Fabbri M, Fantinati A, et al.
J Med Chem
. 2021 Mar;
64(7):4089-4108.
PMID: 33733768
Neuropeptide S modulates important neurobiological functions including locomotion, anxiety, and drug abuse through interaction with its G protein-coupled receptor known as neuropeptide S receptor (NPSR). NPSR antagonists are potentially useful...