Sebastiaan H Meijsing
Overview
Explore the profile of Sebastiaan H Meijsing including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
27
Citations
1035
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0
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Recent Articles
21.
Thomas-Chollier M, Watson L, Cooper S, Pufall M, Liu J, Borzym K, et al.
Proc Natl Acad Sci U S A
. 2013 Oct;
110(44):17826-31.
PMID: 24127590
In addition to guiding proteins to defined genomic loci, DNA can act as an allosteric ligand that influences protein structure and activity. Here we compared genome-wide binding, transcriptional regulation, and,...
22.
Prykhozhij S, Marsico A, Meijsing S
Zebrafish
. 2013 May;
10(3):303-15.
PMID: 23656298
The zebrafish (Danio rerio) is an established model organism for developmental and biomedical research. It is frequently used for high-throughput functional genomics experiments, such as genome-wide gene expression measurements, to...
23.
DeKelver R, Choi V, Moehle E, Paschon D, Hockemeyer D, Meijsing S, et al.
Genome Res
. 2010 May;
20(8):1133-42.
PMID: 20508142
Isogenic settings are routine in model organisms, yet remain elusive for genetic experiments on human cells. We describe the use of designed zinc finger nucleases (ZFNs) for efficient transgenesis without...
24.
Meijsing S, Pufall M, So A, Bates D, Chen L, Yamamoto K
Science
. 2009 Apr;
324(5925):407-10.
PMID: 19372434
Genes are not simply turned on or off, but instead their expression is fine-tuned to meet the needs of a cell. How genes are modulated so precisely is not well...
25.
Meijsing S, Elbi C, Luecke H, Hager G, Yamamoto K
Mol Cell Biol
. 2007 Jan;
27(7):2442-51.
PMID: 17261597
Ligand binding to the glucocorticoid receptor (GR) results in receptor binding to glucocorticoid response elements (GREs) and the formation of transcriptional regulatory complexes. Equally important, these complexes are continuously disassembled,...
26.
Wang J, Shah N, Pantoja C, Meijsing S, Ho J, Scanlan T, et al.
Genes Dev
. 2006 Mar;
20(6):689-99.
PMID: 16543221
The activities of intracellular receptors are regulated by their cognate ligands. Here we show that a series of related arylpyrazole compounds, which specifically bind the glucocorticoid receptor (GR), selectively modulated...
27.
Schaper S, Franke J, Meijsing S, Ehrenhofer-Murray A
J Cell Sci
. 2005 Mar;
118(Pt 7):1473-84.
PMID: 15788653
The protein complex SAS-I links histone acetylation to the assembly of repressed chromatin in Saccharomyces cerevisiae. Sas2p, the histone acetyltransferase subunit of SAS-I, forms a complex with Sas4p and Sas5p,...