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Sean L Seymour

Explore the profile of Sean L Seymour including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 3179
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Recent Articles
1.
Binz P, Shofstahl J, Vizcaino J, Barsnes H, Chalkley R, Menschaert G, et al.
J Proteome Res . 2019 May; 18(6):2686-2692. PMID: 31081335
Mass-spectrometry-based proteomics enables the high-throughput identification and quantification of proteins, including sequence variants and post-translational modifications (PTMs) in biological samples. However, most workflows require that such variations be included in...
2.
Seymour S, Farrah T, Binz P, Chalkley R, Cottrell J, Searle B, et al.
Proteomics . 2014 Aug; 14(21-22):2389-99. PMID: 25092112
Inferring which protein species have been detected in bottom-up proteomics experiments has been a challenging problem for which solutions have been maturing over the past decade. While many inference approaches...
3.
Jagtap P, Goslinga J, Kooren J, McGowan T, Wroblewski M, Seymour S, et al.
Proteomics . 2013 Feb; 13(8):1352-7. PMID: 23412978
Large databases (>10(6) sequences) used in metaproteomic and proteogenomic studies present challenges in matching peptide sequences to MS/MS data using database-search programs. Most notably, strict filtering to avoid false-positive matches...
4.
Chambers M, MacLean B, Burke R, Amodei D, Ruderman D, Neumann S, et al.
Nat Biotechnol . 2012 Oct; 30(10):918-20. PMID: 23051804
No abstract available.
5.
Jagtap P, Bandhakavi S, Higgins L, McGowan T, Sa R, Stone M, et al.
Proteomics . 2012 May; 12(11):1726-30. PMID: 22623410
LTQ Orbitrap data analyzed with ProteinPilot can be further improved by MaxQuant raw data processing, which utilizes precursor-level high mass accuracy data for peak processing and MGF creation. In particular,...
6.
Jones A, Eisenacher M, Mayer G, Kohlbacher O, Siepen J, Hubbard S, et al.
Mol Cell Proteomics . 2012 Mar; 11(7):M111.014381. PMID: 22375074
We report the release of mzIdentML, an exchange standard for peptide and protein identification data, designed by the Proteomics Standards Initiative. The format was developed by the Proteomics Standards Initiative...
7.
Kinsinger C, Apffel J, Baker M, Bian X, Borchers C, Bradshaw R, et al.
Proteomics Clin Appl . 2012 Jan; 5(11-12):580-9. PMID: 22213554
Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data...
8.
Kinsinger C, Apffel J, Baker M, Bian X, Borchers C, Bradshaw R, et al.
Proteomics . 2011 Nov; 12(1):11-20. PMID: 22069307
Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data...
9.
Kinsinger C, Apffel J, Baker M, Bian X, Borchers C, Bradshaw R, et al.
J Proteome Res . 2011 Nov; 11(2):1412-9. PMID: 22053864
Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data...
10.
Kinsinger C, Apffel J, Baker M, Bian X, Borchers C, Bradshaw R, et al.
Mol Cell Proteomics . 2011 Nov; 10(12):O111.015446. PMID: 22052993
Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data...