Sean L Seymour
Overview
Explore the profile of Sean L Seymour including associated specialties, affiliations and a list of published articles.
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20
Citations
3179
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Recent Articles
11.
Tambor V, Hunter C, Seymour S, Kacerovsky M, Stulik J, Lenco J
J Proteomics
. 2011 Oct;
75(3):857-67.
PMID: 22008608
Shotgun proteomics is capable of characterizing differences in both protein quality and quantity, and has been applied in various biomedical applications. Unfortunately, the high complexity and dynamic range of proteins...
12.
Thomson S, Petti F, Sujka-Kwok I, Mercado P, Bean J, Monaghan M, et al.
Clin Exp Metastasis
. 2011 Jan;
28(2):137-55.
PMID: 21194007
Epithelial-mesenchymal transition (EMT) is an important contributor to the invasion and metastasis of epithelial-derived cancers. While considerable effort has focused in the regulators involved in the transition process, we have...
13.
Tang W, Shilov I, Seymour S
J Proteome Res
. 2008 Aug;
7(9):3661-7.
PMID: 18700793
False discovery rate (FDR) analyses of protein and peptide identification results using decoy database searching conventionally report aggregate or global FDRs for a whole set of identifications, which are often...
14.
Montecchi-Palazzi L, Beavis R, Binz P, Chalkley R, Cottrell J, Creasy D, et al.
Nat Biotechnol
. 2008 Aug;
26(8):864-6.
PMID: 18688235
No abstract available.
15.
Binz P, Barkovich R, Beavis R, Creasy D, Horn D, Julian Jr R, et al.
Nat Biotechnol
. 2008 Aug;
26(8):862.
PMID: 18688233
No abstract available.
16.
Taylor C, Binz P, Aebersold R, Affolter M, Barkovich R, Deutsch E, et al.
Nat Biotechnol
. 2008 Aug;
26(8):860-1.
PMID: 18688232
No abstract available.
17.
Taylor C, Paton N, Lilley K, Binz P, Julian Jr R, Jones A, et al.
Nat Biotechnol
. 2007 Aug;
25(8):887-93.
PMID: 17687369
Both the generation and the analysis of proteomics data are now widespread, and high-throughput approaches are commonplace. Protocols continue to increase in complexity as methods and technologies evolve and diversify....
18.
Shilov I, Seymour S, Patel A, Loboda A, Tang W, Keating S, et al.
Mol Cell Proteomics
. 2007 May;
6(9):1638-55.
PMID: 17533153
The Paragon Algorithm, a novel database search engine for the identification of peptides from tandem mass spectrometry data, is presented. Sequence Temperature Values are computed using a sequence tag algorithm,...
19.
Tang W, Halpern B, Shilov I, Seymour S, Keating S, Loboda A, et al.
Anal Chem
. 2005 Jul;
77(13):3931-46.
PMID: 15987094
We present an MS/MS database search algorithm with the following novel features: (1) a novel protein database structure containing extensive preindexing and (2) zone modification searching, which enables the rapid...
20.
Seymour S, Klinman J
Biochemistry
. 2002 Jul;
41(27):8747-58.
PMID: 12093294
An earlier investigation of the temperature dependencies of rates and kinetic isotope effects (KIEs) in glucose oxidase (GO) used variants that differed in the extent of glycosylation at the surface...