Stephen E Stein
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Explore the profile of Stephen E Stein including associated specialties, affiliations and a list of published articles.
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83
Citations
1821
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Recent Articles
1.
Singh S, Liu Y, Burke M, Rayaprolu V, Stein S, Hasan S
J Struct Biol X
. 2025 Mar;
11:100123.
PMID: 40046771
The SARS-CoV-2 spike protein is synthesized in the endoplasmic reticulum of host cells, from where it undergoes export to the Golgi and the plasma membrane or retrieval from the Golgi...
2.
McGlynn D, Yee L, Garraffo H, Geer L, Mak T, Mirokhin Y, et al.
J Am Soc Mass Spectrom
. 2025 Jan;
36(2):389-399.
PMID: 39806561
While gas chromatography mass spectrometry (GC-MS) has long been used to identify compounds in complex mixtures, this process is often subjective and time-consuming and leaves a large fraction of seemingly...
3.
Simon-Manso Y, Erisman E, Mak T, Burke M, Zuber A, Yang X, et al.
J Am Soc Mass Spectrom
. 2025 Jan;
36(2):439-445.
PMID: 39752563
The Mass Spectrometry Data Center (MSDC) has recently started improving existing libraries and creating new ones for identifying and analyzing plastics-related compounds (PRC) and materials (PRM) as part of the...
4.
Liang Y, Neta P, Yang X, Garraffo H, Bukhari T, Liu Y, et al.
J Am Soc Mass Spectrom
. 2024 Nov;
36(1):85-90.
PMID: 39574372
Peak annotation plays an important role in mass spectral evaluation of the NIST 2023 tandem mass spectral library. While most fragment ions are formed by neutral losses, there are peaks...
5.
Goecker Z, Burke M, Remoroza C, Liu Y, Mirokhin Y, Sheetlin S, et al.
Mol Cell Proteomics
. 2024 Aug;
23(9):100827.
PMID: 39128790
This work presents a detailed determination of site-specific N-glycan distributions of the recombinant influenza glycoproteins hemagglutinin (HA) and neuraminidase. Variation in glycosylation among recombinant glycoproteins is not predictable and can...
6.
Wang G, Zhang Z, Liu Y, Burke M, Sheetlin S, Stein S
J Proteome Res
. 2024 Apr;
23(5):1571-1582.
PMID: 38594959
Reproducibility is a "proteomic dream" yet to be fully realized. A typical data analysis workflow utilizing extracted ion chromatograms (XICs) often treats the information path from identification to quantification as...
7.
Remoroza C, Burke M, Mak T, Sheetlin S, Mirokhin Y, Cooper B, et al.
J Proteome Res
. 2024 Mar;
23(4):1443-1457.
PMID: 38450643
We report the comparison of mass-spectral-based abundances of tryptic glycopeptides to fluorescence abundances of released labeled glycans and the effects of mass and charge state and in-source fragmentation on glycopeptide...
8.
Geer L, Stein S, Mallard W, Slotta D
J Chem Inf Model
. 2024 Jan;
64(3):690-696.
PMID: 38230885
The Kováts retention index (RI) is a quantity measured using gas chromatography and is commonly used in the identification of chemical structures. Creating libraries of observed RI values is a...
9.
Zhang Z, Wallace W, Wang G, Burke M, Liu Y, Sheetlin S, et al.
J Proteome Res
. 2023 Nov;
23(1):409-417.
PMID: 38009783
A fast and sensitive direct extraction (DE) method developed in our group can efficiently extract proteins in 30 min from a 5 cm-long hair strand. Previously, we coupled DE to...
10.
Burke M, Liu Y, Remoroza C, Mirokhin Y, Sheetlin S, Tchekhovskoi D, et al.
J Proteome Res
. 2023 Aug;
22(10):3225-3241.
PMID: 37647588
Glycopeptide Abundance Distribution Spectra (GADS) were recently introduced as a means of representing, storing, and comparing glycan profiles of intact glycopeptides. Here, using that representation, an extensive analysis is made...