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» Authors » Seamas C Donnelly

Seamas C Donnelly

Explore the profile of Seamas C Donnelly including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 136
Citations 2184
Followers 0
Related Specialties
General Medicine
Allergy & Immunology
Pulmonary Medicine
Top 10 Co-Authors
Michelle E Armstrong
Gordon Cooke
Mohammad Doroudian
John A Baugh
Michael P Keane
David N ODwyer
Richard Bucala
Clare M OConnor
Ian J Hawthorne
Ann B Millar
Published In
QJM
Am J Respir Crit Care Med
J Immunol
FASEB J
Thorax
Affiliations
Soon will be listed here.
Recent Articles
11.
A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus
Li J, Leng L, Pantouris G, Manjula R, Piecychna M, Abriola L, et al.
J Biol Chem . 2024 Jun; 300(7):107443. PMID: 38838773
Functional variants of the gene for the cytokine macrophage migration inhibitory factor (MIF) are defined by a 4-nucleotide promoter microsatellite (-794 CATT, rs5844572) and confer risk for autoimmune, infectious, and...
12.
Mesenchymal stromal cells dampen trained immunity in house dust mite-primed macrophages expressing human macrophage migration inhibitory factor polymorphism
Dunbar H, Hawthorne I, Tunstead C, McNamee E, Weiss D, Armstrong M, et al.
Cytotherapy . 2024 May; 26(10):1245-1251. PMID: 38819366
Background: Trained immunity results in long-term immunological memory, provoking a faster and greater immune response when innate immune cells encounter a secondary, often heterologous, stimulus. We have previously shown that...
13.
Early life, biological ageing and subsequent disease susceptibility in later years
Donnelly S
QJM . 2024 Apr; 117(4):241. PMID: 38608182
No abstract available.
14.
The Association of Physicians of Great Britain and Ireland (AoPGBI) annual conference at Newcastle University: 23-24 May 2024. Celebrating the latest and very best of translational medicine
Donnelly S
QJM . 2024 Mar; 117(3):161-162. PMID: 38538327
No abstract available.
15.
The human MIF polymorphism CATT enhances pro-inflammatory macrophage polarization in a clinically relevant model of allergic airway inflammation
Dunbar H, Hawthorne I, McNamee E, Armstrong M, Donnelly S, English K
FASEB J . 2024 Mar; 38(6):e23576. PMID: 38530238
High level expression of the pro-inflammatory cytokine macrophage migration inhibitory factor (MIF) has been associated with severe asthma. The role of MIF and its functional promotor polymorphism in innate immune...
16.
Multimorbidity post COVID-19 acute infection: evidence that COVID-19 vaccination protects you
Donnelly S
QJM . 2024 Feb; 117(2):93. PMID: 38408373
No abstract available.
17.
The Long-COVID Syndrome-how to assess in real-time an individuals well-being-the COVID-19 Yorkshire Rehabilitation Scale (C19-YRSm)
Donnelly S
QJM . 2024 Feb; 117(1):1. PMID: 38326099
No abstract available.
18.
Tick-borne encephalitis-a substantial increase in cases in Western Europe
Donnelly S
QJM . 2023 Dec; 116(12):971. PMID: 38153003
No abstract available.
19.
Mental health in healthcare workers and patient families in these COVID times
Donnelly S
QJM . 2023 Nov; 116(11):893. PMID: 38006216
No abstract available.
20.
Human macrophage migration inhibitory factor potentiates mesenchymal stromal cell efficacy in a clinically relevant model of allergic asthma
Hawthorne I, Dunbar H, Tunstead C, Schorpp T, Weiss D, Rolandsson Enes S, et al.
Mol Ther . 2023 Sep; 31(11):3243-3258. PMID: 37735872
Current asthma therapies focus on reducing symptoms but fail to restore existing structural damage. Mesenchymal stromal cell (MSC) administration can ameliorate airway inflammation and reverse airway remodeling. However, differences in...