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Scott Van Buren

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Articles 7
Citations 81
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Recent Articles
1.
Young A, Van Buren S, Rashid N
Biostatistics . 2023 Apr; 25(2):559-576. PMID: 37040757
Differential transcript usage (DTU) occurs when the relative expression of multiple transcripts arising from the same gene changes between different conditions. Existing approaches to detect DTU often rely on computational...
2.
Innocenti F, Yazdani A, Rashid N, Qu X, Ou F, Van Buren S, et al.
Clin Cancer Res . 2022 Feb; 28(8):1690-1700. PMID: 35176136
Purpose: CALGB/SWOG 80405 was a randomized phase III trial in first-line patients with metastatic colorectal cancer treated with bevacizumab, cetuximab, or both, plus chemotherapy. We tested the effect of tumor...
3.
Van Buren S, Sarkar H, Srivastava A, Rashid N, Patro R, Love M
Bioinformatics . 2021 Jan; 37(12):1699-1707. PMID: 33471073
Motivation: Quantification estimates of gene expression from single-cell RNA-seq (scRNA-seq) data have inherent uncertainty due to reads that map to multiple genes. Many existing scRNA-seq quantification pipelines ignore multi-mapping reads...
4.
Lewis M, Flynn M, Lee E, Van Buren S, Van Buren E, Du G, et al.
Neurotoxicology . 2016 Aug; 57:39-44. PMID: 27567731
Objectives: We demonstrated recently that the T1 relaxation rate (R1) captured short-term Mn exposure in welders with chronic, relatively low exposure levels in a cross-sectional study. In the current study,...
5.
Lee E, Flynn M, Du G, Lewis M, Herring A, Van Buren E, et al.
Toxicol Sci . 2016 Jul; 153(1):165-73. PMID: 27466214
Introduction: Welding fumes contain several metals including manganese (Mn), iron (Fe), and copper (Cu) that at high exposure may co-influence welding-related neurotoxicity. The relationship between brain accumulation of these metals...
6.
Lee E, Flynn M, Du G, Li Y, Lewis M, Herring A, et al.
Toxicol Sci . 2016 Jan; 150(2):369-77. PMID: 26769335
Welding has been associated with neurobehavioral disorders. Welding fumes contain several metals including copper (Cu), manganese (Mn), and iron (Fe) that may interact to influence welding-related neurotoxicity. Although welding-related airborne...
7.
Lee E, Flynn M, Du G, Lewis M, Fry R, Herring A, et al.
Toxicol Sci . 2015 May; 146(2):281-9. PMID: 25953701
Although the essential element manganese (Mn) is neurotoxic at high doses, the effects of lower exposure are unclear. MRI T1-weighted (TIW) imaging has been used to estimate brain Mn exposure...