Michael R Flynn
Overview
Explore the profile of Michael R Flynn including associated specialties, affiliations and a list of published articles.
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30
Citations
307
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Recent Articles
1.
Lee E, Flynn M, Du G, Lewis M, Goldenberg M, Kong L, et al.
Parkinsonism Relat Disord
. 2021 Mar;
85:37-43.
PMID: 33691274
Introduction: Manganese (Mn)-induced parkinsonism involves motor symptoms similar to those observed in Parkinson's disease (PD). Previous literature suggests that chronic Mn- exposure may increase PD risk, although Mn-induced clinical syndromes...
2.
Lee E, Flynn M, Du G, Lewis M, Kong L, Yanosky J, et al.
Toxicol Sci
. 2019 Jan;
168(2):486-496.
PMID: 30629252
Chronic high-level manganese (Mn)-induced neurotoxicity has been associated with Mn accumulation in the basal ganglia and higher risk for developing parkinsonism. Recent studies in Mn-exposed animals revealed Mn accumulation in...
3.
Lee E, Flynn M, Lewis M, Mailman R, Huang X
Neurotoxicology
. 2017 Jun;
64:50-59.
PMID: 28648949
Although an essential nutrient, manganese (Mn) can be toxic at high doses. There is, however, uncertainty regarding the effects of chronic low-level Mn-exposure. This review provides an overview of Mn-related...
4.
Lee E, Eslinger P, Flynn M, Wagner D, Du G, Lewis M, et al.
Neurotoxicology
. 2016 Nov;
58:66-74.
PMID: 27871916
Objectives: Welding fumes contain several metals including manganese (Mn) and iron (Fe) that may affect the nervous system. Previous studies of potential welding-related neurotoxicity have focused primarily on Mn exposure....
5.
Lewis M, Flynn M, Lee E, Van Buren S, Van Buren E, Du G, et al.
Neurotoxicology
. 2016 Aug;
57:39-44.
PMID: 27567731
Objectives: We demonstrated recently that the T1 relaxation rate (R1) captured short-term Mn exposure in welders with chronic, relatively low exposure levels in a cross-sectional study. In the current study,...
6.
Lee E, Flynn M, Du G, Lewis M, Herring A, Van Buren E, et al.
Toxicol Sci
. 2016 Jul;
153(1):165-73.
PMID: 27466214
Introduction: Welding fumes contain several metals including manganese (Mn), iron (Fe), and copper (Cu) that at high exposure may co-influence welding-related neurotoxicity. The relationship between brain accumulation of these metals...
7.
Lewis M, Lee E, Jo H, Du G, Park J, Flynn M, et al.
Neurotoxicology
. 2016 Jul;
56:76-85.
PMID: 27373673
Background: Multi-digit synergies, a recently developed, theory-based method to quantify stability of motor action, are shown to reflect basal ganglia dysfunction associated with parkinsonian syndromes. In this study, we tested...
8.
Lee E, Flynn M, Du G, Li Y, Lewis M, Herring A, et al.
Toxicol Sci
. 2016 Jan;
150(2):369-77.
PMID: 26769335
Welding has been associated with neurobehavioral disorders. Welding fumes contain several metals including copper (Cu), manganese (Mn), and iron (Fe) that may interact to influence welding-related neurotoxicity. Although welding-related airborne...
9.
Lee E, Flynn M, Du G, Lewis M, Fry R, Herring A, et al.
Toxicol Sci
. 2015 May;
146(2):281-9.
PMID: 25953701
Although the essential element manganese (Mn) is neurotoxic at high doses, the effects of lower exposure are unclear. MRI T1-weighted (TIW) imaging has been used to estimate brain Mn exposure...
10.
Flynn M, Susi P
Ann Occup Hyg
. 2012 Mar;
56(7):764-76.
PMID: 22459321
Arc welding is a common unit operation in the construction industry, where frequent changes in location and welding position make it more difficult to control fume exposures than in industries...