Richard B Mailman
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Explore the profile of Richard B Mailman including associated specialties, affiliations and a list of published articles.
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90
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2417
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Recent Articles
1.
Bargues-Carot A, Prado-Rico J, Kawasawa Y, Cai J, Yanosky J, Zenitsky G, et al.
medRxiv
. 2025 Feb;
PMID: 39990579
Chronic occupational exposure to metals in welding fumes has been implicated in the etiology of neurodegenerative diseases (NDDs), including Parkinson's disease (PD) and Alzheimer's disease (AD). Changes in microRNA (miRNA)...
2.
Lewis M, Mailman R, Cheng X, Du G, Zhang L, Li C, et al.
Parkinsonism Relat Disord
. 2024 Nov;
130:107186.
PMID: 39541725
Background: Parkinson's disease (PD) therapeutic strategies have evolved since levodopa introduction in mid 1900s. To understand their impact and research gaps, this study delineated the clinical progression of PD in...
3.
Lee E, Kim J, Prado-Rico J, Du G, Lewis M, Kong L, et al.
Neurotoxicology
. 2024 Oct;
105:196-207.
PMID: 39395642
Background: Environmental exposure to metal mixtures is common and may be associated with increased risk for neurodegenerative disorders including Alzheimer's disease. This study examined associations of mixed metal exposures with...
4.
Wang J, Ekambaram S, Huang X, Mailman R, Proctor E, Dokholyan N
bioRxiv
. 2024 Sep;
PMID: 39345474
Levodopa remains the primary treatment for Parkinson's disease (PD), yet its long-term use has been associated with iron accumulation in the brain, a phenomenon linked to neurodegeneration. We utilize deep...
5.
Sha C, Wang J, Mailman R, Yang Y, Dokholyan N
Front Comput Neurosci
. 2024 Sep;
18:1293279.
PMID: 39268151
The question of how consciousness and behavior arise from neural activity is fundamental to understanding the brain, and to improving the diagnosis and treatment of neurological and psychiatric disorders. There...
6.
De Jesus S, Daya A, Blumberger L, Lewis M, Leslie D, Tabbal S, et al.
Mov Disord
. 2024 Jul;
39(9):1592-1601.
PMID: 38962960
Background: Patients in late-stage Parkinson's disease (PD) are caregiver-dependent, have low quality of life, and higher healthcare costs. Objective: To estimate the prevalence of PD patients in the current US...
7.
Bransom L, Bassett A, Zhou M, Cimino J, Mailman R, Yang Y
Neuroscience
. 2024 Jun;
551:177-184.
PMID: 38823551
Dopamine D receptor agonists improve spatial working memory, but their effects on temporal order memory, particularly prone to the effects of aging, have not been studied. Two D agonists, PF6256142...
8.
Han F, Liu X, Mailman R, Huang X, Liu X
Nat Commun
. 2023 Nov;
14(1):7788.
PMID: 38012153
It remains unclear why β-amyloid (Aβ) plaque, a hallmark pathology of Alzheimer's disease (AD), first accumulates cortically in the default mode network (DMN), years before AD diagnosis. Resting-state low-frequency ( ...
9.
Foy A, Vrana K, Haidet P, Hausman B, Adams N, Ropson I, et al.
Adv Med Educ Pract
. 2023 Sep;
14:989-998.
PMID: 37724185
Purpose: Critical thinking and the ability to engage with others of differing views in a civil manner is essential to the practice of medicine. A new format for medical student...
10.
Cimino J, Zhou M, Waxmonsky J, Mailman R, Yang Y
Psychopharmacology (Berl)
. 2023 Aug;
240(10):2187-2199.
PMID: 37578525
Rationale: Dopamine D receptor agonists have been shown to improve working memory, but often have a non-monotonic (inverted-U) dose-response curve. One hypothesis is that this may reflect dose-dependent differential engagement...