Scott Hiebert
Overview
Explore the profile of Scott Hiebert including associated specialties, affiliations and a list of published articles.
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10
Citations
573
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Recent Articles
1.
Williams C, Brown R, Zhao Y, Wang J, Chen Z, Blunt K, et al.
Res Sq
. 2023 Oct;
PMID: 37790452
Undifferentiated intestinal stem cells (ISCs), particularly those marked by , are crucial for maintaining homeostasis and resolving injury. + cells in the crypt base constantly divide, pushing daughter cells upward...
2.
Ramsey H, Stengel K, Pino J, Johnston G, Childress M, Gorska A, et al.
Target Oncol
. 2021 Jul;
16(5):663-674.
PMID: 34324169
Background: All-trans retinoic acid (ATRA), a derivate of vitamin A, has been successfully used as a therapy to induce differentiation in M3 acute promyelocytic leukemia (APML), and has led to...
3.
Boothby M, Raybuck A, Cho S, Stengel K, Haase V, Hiebert S, et al.
Front Immunol
. 2021 May;
12:664249.
PMID: 34040610
Accumulating evidence suggests that many immune responses are influenced by local nutrient concentrations in addition to the programming of intermediary metabolism within immune cells. Humoral immunity and germinal centers (GC)...
4.
Davalos-Salas M, Montgomery M, Reehorst C, Nightingale R, Ng I, Anderton H, et al.
Nat Commun
. 2019 Nov;
10(1):5291.
PMID: 31757939
Histone deacetylase 3 (Hdac3) regulates the expression of lipid metabolism genes in multiple tissues, however its role in regulating lipid metabolism in the intestinal epithelium is unknown. Here we demonstrate...
5.
Cho S, Raybuck A, Stengel K, Wei M, Beck T, Volanakis E, et al.
Nature
. 2016 Aug;
537(7619):234-238.
PMID: 27501247
Germinal centres (GCs) promote humoral immunity and vaccine efficacy. In GCs, antigen-activated B cells proliferate, express high-affinity antibodies, promote antibody class switching, and yield B cell memory. Whereas the cytokine...
6.
Chan E, Arlinghaus L, Cardin D, Goff L, Berlin J, Parikh A, et al.
Radiother Oncol
. 2016 Apr;
119(2):312-8.
PMID: 27106554
Background And Purpose: This single institution phase I trial determined the maximum tolerated dose (MTD) of concurrent vorinostat and capecitabine with radiation in non-metastatic pancreatic cancer. Material And Methods: Twenty-one...
7.
Ha K, Fiskus W, Choi D, Bhaskara S, Cerchietti L, Devaraj S, et al.
Oncotarget
. 2014 Jul;
5(14):5637-50.
PMID: 25026298
There is an unmet need to develop new, more effective and safe therapies for the aggressive forms of triple negative breast cancers (TNBCs). While up to 20% of women under...
8.
Yan L, Womack B, Wotton D, Guo Y, Shyr Y, Dave U, et al.
Mol Cell Biol
. 2013 Oct;
33(24):4824-33.
PMID: 24100014
TG-interacting factor 1 (TGIF1) is a transcriptional repressor that can modulate retinoic acid and transforming growth factor β signaling pathways. It is required for myeloid progenitor cell differentiation and survival,...
9.
Thapa P, Das J, McWilliams D, Shapiro M, Sundsbak R, Nelson-Holte M, et al.
Nat Commun
. 2013 Mar;
4:1582.
PMID: 23481390
Invariant natural killer T cells have a distinct developmental pathway from conventional αβ T cells. Here we demonstrate that the transcriptional repressor NKAP is required for invariant natural killer T...
10.
Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, et al.
Proc Natl Acad Sci U S A
. 2012 Jul;
109(42):E2865-74.
PMID: 22802645
Histone deacetylases (HDACs) regulate inflammatory gene expression, as indicated by the potent antiinflammatory activity of pan-HDAC inhibitors. However, the specific contribution of each of the 11 HDAC proteins to the...