Santhana G T Devaraj
Overview
Explore the profile of Santhana G T Devaraj including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
344
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Recent Articles
1.
Sun B, Shah B, Fiskus W, Qi J, Rajapakshe K, Coarfa C, et al.
Blood
. 2015 Aug;
126(13):1565-74.
PMID: 26254443
Mantle cell lymphoma (MCL) cells exhibit increased B-cell receptor and nuclear factor (NF)-κB activities. The bromodomain and extra-terminal (BET) protein bromodomain 4 is essential for the transcriptional activity of NF-κB....
2.
Fiskus W, Sharma S, Qi J, Shah B, Devaraj S, Leveque C, et al.
Mol Cancer Ther
. 2014 Jul;
13(10):2315-27.
PMID: 25053825
Recently, treatment with bromodomain and extraterminal protein antagonist (BA) such as JQ1 has been shown to inhibit growth and induce apoptosis of human acute myelogenous leukemia (AML) cells, including those...
3.
Ha K, Fiskus W, Choi D, Bhaskara S, Cerchietti L, Devaraj S, et al.
Oncotarget
. 2014 Jul;
5(14):5637-50.
PMID: 25026298
There is an unmet need to develop new, more effective and safe therapies for the aggressive forms of triple negative breast cancers (TNBCs). While up to 20% of women under...
4.
Fiskus W, Sharma S, Qi J, Valenta J, Schaub L, Shah B, et al.
Mol Cancer Ther
. 2014 Jan;
13(5):1142-54.
PMID: 24435446
The bromodomain and extra-terminal (BET) protein family members, including BRD4, bind to acetylated lysines on histones and regulate the expression of important oncogenes, for example, c-MYC and BCL2. Here, we...