Scott H Randell
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Explore the profile of Scott H Randell including associated specialties, affiliations and a list of published articles.
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199
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13632
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Recent Articles
1.
Saferali A, Wienecke A, Xu Z, Liu T, Sheynkman G, Hersh C, et al.
Eur Respir J
. 2025 Feb;
PMID: 39978861
Background: Identification of COPD disease-causing genes is an important tool for understanding why COPD develops, who is at highest COPD risk, and how new COPD treatments can be developed. Previous...
2.
Mwase C, Schworer S, Gilmore R, Khan F, Dy A, Haber A, et al.
Am J Respir Cell Mol Biol
. 2025 Jan;
PMID: 39773168
In asthma, tissue factor (TF) levels are elevated in the lung. In our previous studies using mechanically compressed human bronchial epithelial (HBE) cells, which are a well-defined in vitro model...
3.
Ghosh A, Rogers Jr K, Gallant S, Brocke S, Speen A, Kim Y, et al.
Toxicol Sci
. 2024 Dec;
204(1):2-8.
PMID: 39673801
Inhalation of smoke from burn pits during military deployment is associated with several adverse pulmonary outcomes. We exposed human airway epithelial cells to smoke condensates from burn pit waste materials....
4.
Lehmann M, Krishnan R, Sucre J, Kulkarni H, Pineda R, Anderson C, et al.
Am J Respir Cell Mol Biol
. 2024 Nov;
PMID: 39499861
The urgent need for effective treatments for acute and chronic lung diseases underscores the significance of developing innovative preclinical human research tools. The 2023 ATS Workshop on Precision Cut Lung...
5.
Pickles R, Chen G, Randell S
J Clin Invest
. 2024 Nov;
134(21).
PMID: 39484717
Immature innate and adaptive immunity and vulnerability of narrower airways to obstruction increase the susceptibility of infants to severe respiratory syncytial virus (RSV) disease. In this issue of the JCI,...
6.
Polybacterial Intracellular Macromolecules Shape Single-Cell Epikine Profiles in Upper Airway Mucosa
Easter Q, Alvarado-Martinez Z, Kunz M, Fernandes Matuck B, Rupp B, Weaver T, et al.
bioRxiv
. 2024 Oct;
PMID: 39416216
The upper airway, particularly the nasal and oral mucosal epithelium, serves as a primary barrier for microbial interactions throughout life. Specialized niches like the anterior nares and the tooth are...
7.
Ghosh A, Rogers Jr K, Gallant S, Kim Y, Rager J, Gilmour M, et al.
Part Fibre Toxicol
. 2024 Oct;
21(1):41.
PMID: 39380034
Background: Exposure to military burn pit smoke during deployment is associated with different respiratory and non-respiratory diseases. However, information linking smoke exposure to human pulmonary health is lacking. This study...
8.
Cheng C, Katoch P, Zhong Y, Higgins C, Moredock M, Chang M, et al.
Int J Mol Sci
. 2024 Sep;
25(18).
PMID: 39337350
The basal cell maintains the airway's respiratory epithelium as the putative resident stem cell. Basal cells are known to self-renew and differentiate into airway ciliated and secretory cells. However, it...
9.
Sun L, Walls S, Dang H, Quinney N, Sears P, Sadritabrizi T, et al.
bioRxiv
. 2024 Aug;
PMID: 39211176
Rationale: Hyper IgE syndrome (STAT3-HIES), also known as Job's syndrome, is a rare immunodeficiency disease typically caused by dominant-negative STAT3 mutations. STAT3-HIES syndrome is characterized by chronic pulmonary infection and...
10.
Liang K, Barnett K, Hsu M, Chou W, Bais S, Riebe K, et al.
Sci Immunol
. 2024 Jul;
9(97):eadn0178.
PMID: 38996010
Virus-induced cell death is a key contributor to COVID-19 pathology. Cell death induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is well studied in myeloid cells but less in...