Rodney C Gilmore
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Explore the profile of Rodney C Gilmore including associated specialties, affiliations and a list of published articles.
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28
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1311
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Recent Articles
1.
Mwase C, Schworer S, Gilmore R, Khan F, Dy A, Haber A, et al.
Am J Respir Cell Mol Biol
. 2025 Jan;
PMID: 39773168
In asthma, tissue factor (TF) levels are elevated in the lung. In our previous studies using mechanically compressed human bronchial epithelial (HBE) cells, which are a well-defined in vitro model...
2.
Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis
Asakura T, Okuda K, Chen G, Dang H, Kato T, Mikami Y, et al.
Am J Respir Crit Care Med
. 2023 Nov;
209(4):374-389.
PMID: 38016030
Non-cystic fibrosis bronchiectasis (NCFB) may originate in bronchiolar regions of the lung. Accordingly, there is a need to characterize the morphology and molecular characteristics of NCFB bronchioles. Test the hypothesis...
3.
Mikami Y, Grubb B, Rogers T, Dang H, Asakura T, Kota P, et al.
Sci Transl Med
. 2023 Jun;
15(699):eabo7728.
PMID: 37285404
Unlike solid organs, human airway epithelia derive their oxygen from inspired air rather than the vasculature. Many pulmonary diseases are associated with intraluminal airway obstruction caused by aspirated foreign bodies,...
4.
Barnett K, Xie Y, Asakura T, Song D, Liang K, Taft-Benz S, et al.
Cell Host Microbe
. 2022 Dec;
31(2):243-259.e6.
PMID: 36563691
Elevated levels of cytokines IL-1β and IL-6 are associated with severe COVID-19. Investigating the underlying mechanisms, we find that while primary human airway epithelia (HAE) have functional inflammasomes and support...
5.
Goriounova A, Gilmore R, Wrennall J, Tarran R
J Cyst Fibros
. 2022 Aug;
22(1):161-171.
PMID: 35961837
Question: In diseases such as asthma and cystic fibrosis (CF), the immune response is dysregulated and the lung is chronically inflamed. Orai1 activation is required for the initiation and persistence...
6.
Biering S, Sarnik S, Wang E, Zengel J, Leist S, Schafer A, et al.
Nat Genet
. 2022 Jul;
54(8):1078-1089.
PMID: 35879412
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of symptoms in infected individuals, from mild respiratory illness to acute respiratory distress syndrome. A systematic understanding of host factors...
7.
Dinnon 3rd K, Leist S, Okuda K, Dang H, Fritch E, Gully K, et al.
Sci Transl Med
. 2022 Jul;
14(664):eabo5070.
PMID: 35857635
A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PASC), but the mechanistic basis of PASC-associated lung...
8.
Kato T, Asakura T, Edwards C, Dang H, Mikami Y, Okuda K, et al.
Am J Respir Crit Care Med
. 2022 Jul;
206(11):1336-1352.
PMID: 35816430
The incidence and sites of mucus accumulation and molecular regulation of mucin gene expression in coronavirus (COVID-19) lung disease have not been reported. To characterize the incidence of mucus accumulation...
9.
Kato T, Radicioni G, Papanikolas M, Stoychev G, Markovetz M, Aoki K, et al.
Sci Adv
. 2022 Apr;
8(13):eabm9718.
PMID: 35363522
Cystic fibrosis (CF) is characterized by abnormal transepithelial ion transport. However, a description of CF lung disease pathophysiology unifying superficial epithelial and submucosal gland (SMG) dysfunctions has remained elusive. We...
10.
Morrison C, Edwards C, Shaffer K, Araba K, Wykoff J, Williams D, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(16):e2119680119.
PMID: 35353667
Muco-obstructive lung diseases are typically associated with high risks of COVID-19 severity; however, allergic asthma showed reduced susceptibility. To investigate viral spread, primary human airway epithelial (HAE) cell cultures were...