Saumya Jani
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Explore the profile of Saumya Jani including associated specialties, affiliations and a list of published articles.
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14
Citations
84
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Recent Articles
1.
Zeng Z, Zhang T, Zhang J, Li S, Connor S, Zhang B, et al.
Nat Commun
. 2025 Feb;
16(1):1070.
PMID: 39900903
Identifying tumor-specific T cell clones that mediate immunotherapy responses remains challenging. Mutation-associated neoantigen (MANA) -specific CD8+ tumor-infiltrating lymphocytes (TIL) have been shown to express high levels of CXCL13 and CD39...
2.
Pulliam T, Jani S, Goff P, Bhakuni R, Tabachnick-Cherny S, Smythe K, et al.
J Immunother Cancer
. 2024 Oct;
12(10).
PMID: 39401968
Background: Antibodies blocking programmed death (PD)-1 or its ligand (PD-L1) have revolutionized cancer care, but many patients do not experience durable benefits. Novel treatments to stimulate antitumor immunity are needed...
3.
Ryu H, Bi T, Pulliam T, Sarkar K, Church C, Kumar N, et al.
Cell Rep Med
. 2024 Feb;
5(2):101390.
PMID: 38340724
Merkel cell carcinoma is a skin cancer often driven by Merkel cell polyomavirus (MCPyV) with high rates of response to anti-PD-1 therapy despite low mutational burden. MCPyV-specific CD8 T cells...
4.
Pulliam T, Jani S, Jing L, Ryu H, Jojic A, Shasha C, et al.
Cell Rep Med
. 2024 Feb;
5(2):101412.
PMID: 38340723
Understanding cancer immunobiology has been hampered by difficulty identifying cancer-specific T cells. Merkel cell polyomavirus (MCPyV) causes most Merkel cell carcinomas (MCCs). All patients with virus-driven MCC express MCPyV oncoproteins,...
5.
Ford E, Mayer-Blackwell K, Jing L, Laing K, Sholukh A, St Germain R, et al.
Nat Immunol
. 2023 Dec;
25(1):166-177.
PMID: 38057617
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hybrid immunity is more protective than vaccination or previous infection alone. To investigate the kinetics of spike-reactive T (T) cells from SARS-CoV-2 infection...
6.
Jani S, Church C, Nghiem P
Front Immunol
. 2023 Jun;
14:1172913.
PMID: 37287968
Understanding and augmenting cancer-specific immunity is impeded by the fact that most tumors are driven by patient-specific mutations that encode unique antigenic epitopes. The shared antigens in virus-driven tumors can...
7.
Armistead B, Jiang Y, Carlson M, Ford E, Jani S, Houck J, et al.
Mucosal Immunol
. 2023 Jan;
16(1):39-49.
PMID: 36642379
Human breastmilk is rich in T cells; however, their specificity and function are largely unknown. We compared the phenotype, diversity, and antigen specificity of T cells in breastmilk and peripheral...
8.
Ford E, Mayer-Blackwell K, Jing L, Sholukh A, St Germain R, Bossard E, et al.
Res Sq
. 2022 Oct;
PMID: 36263073
Almost three years into the SARS-CoV-2 pandemic, hybrid immunity is highly prevalent worldwide and more protective than vaccination or prior infection alone. Given emerging resistance of variant strains to neutralizing...
9.
Armistead B, Jiang Y, Carlson M, Ford E, Jani S, Houck J, et al.
medRxiv
. 2022 Oct;
PMID: 36203549
One-sentence Summary: The breastmilk T cell repertoire is distinct and enriched for SARS-CoV-2 Spike-specificity after maternal mRNA vaccination.
10.
Jani S, Ramirez M, Tolmasky M
Biomedicines
. 2021 Apr;
9(4).
PMID: 33921367
Antisense technologies consist of the utilization of oligonucleotides or oligonucleotide analogs to interfere with undesirable biological processes, commonly through inhibition of expression of selected genes. This field holds a lot...