Rima Kulikauskas
Overview
Explore the profile of Rima Kulikauskas including associated specialties, affiliations and a list of published articles.
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8
Citations
305
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0
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Recent Articles
1.
Zeng Z, Zhang T, Zhang J, Li S, Connor S, Zhang B, et al.
Nat Commun
. 2025 Feb;
16(1):1070.
PMID: 39900903
Identifying tumor-specific T cell clones that mediate immunotherapy responses remains challenging. Mutation-associated neoantigen (MANA) -specific CD8+ tumor-infiltrating lymphocytes (TIL) have been shown to express high levels of CXCL13 and CD39...
2.
Pulliam T, Jani S, Goff P, Bhakuni R, Tabachnick-Cherny S, Smythe K, et al.
J Immunother Cancer
. 2024 Oct;
12(10).
PMID: 39401968
Background: Antibodies blocking programmed death (PD)-1 or its ligand (PD-L1) have revolutionized cancer care, but many patients do not experience durable benefits. Novel treatments to stimulate antitumor immunity are needed...
3.
Pulliam T, Jani S, Jing L, Ryu H, Jojic A, Shasha C, et al.
Cell Rep Med
. 2024 Feb;
5(2):101412.
PMID: 38340723
Understanding cancer immunobiology has been hampered by difficulty identifying cancer-specific T cells. Merkel cell polyomavirus (MCPyV) causes most Merkel cell carcinomas (MCCs). All patients with virus-driven MCC express MCPyV oncoproteins,...
4.
Mohsin N, Hunt D, Yan J, Jabbour A, Nghiem P, Choi J, et al.
JAMA Dermatol
. 2024 Jan;
160(2):172-178.
PMID: 38170500
Importance: Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer. Of the patients who develop MCC annually, only 4% are younger than 50 years. Objective: To identify genetic...
5.
Topalian S, Bhatia S, Amin A, Kudchadkar R, Sharfman W, Lebbe C, et al.
J Clin Oncol
. 2020 Apr;
38(22):2476-2487.
PMID: 32324435
Purpose: Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer commonly driven by the Merkel cell polyomavirus (MCPyV). The programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) immunosuppressive pathway is often...
6.
Bhatia S, Longino N, Miller N, Kulikauskas R, Iyer J, Ibrani D, et al.
Clin Cancer Res
. 2019 Oct;
26(3):598-607.
PMID: 31582519
Purpose: IL12 promotes adaptive type I immunity and has demonstrated antitumor efficacy, but systemic administration leads to severe adverse events (AE), including death. This pilot trial investigated safety, efficacy, and...
7.
Miller N, Church C, Fling S, Kulikauskas R, Ramchurren N, Shinohara M, et al.
J Immunother Cancer
. 2018 Nov;
6(1):131.
PMID: 30482247
Background: Merkel cell carcinoma (MCC) is an aggressive skin cancer that frequently responds to anti-PD-1 therapy. MCC is associated with sun exposure and, in 80% of cases, Merkel cell polyomavirus...
8.
Bhatia S, Miller N, Lu H, Longino N, Ibrani D, Shinohara M, et al.
Clin Cancer Res
. 2018 Aug;
25(4):1185-1195.
PMID: 30093453
Purpose: G100 is a toll-like receptor 4 (TLR4) agonist that triggers innate and adaptive antitumor immune responses in preclinical models. This pilot study assessed the safety, efficacy, and immunologic activity...
9.
Li Q, Nance M, Kulikauskas R, Nyberg K, Fehon R, Karplus P, et al.
J Mol Biol
. 2006 Dec;
365(5):1446-59.
PMID: 17134719
Ezrin/radixin/moesin (ERM) family members provide a regulated link between the cortical actin cytoskeleton and the plasma membrane to govern membrane structure and organization. Here, we report the crystal structure of...