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Satyanarayana Rachagani

Explore the profile of Satyanarayana Rachagani including associated specialties, affiliations and a list of published articles. Areas
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Articles 107
Citations 3060
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Recent Articles
1.
Kaifi J, Joshi K, Suvilesh K, Natesh N, Manjunath Y, Coberly J, et al.
Res Sq . 2025 Feb; PMID: 39975891
Background: There remains a need for animal models with human translatability in lung cancer (LC) research. Findings in pigs have high impact on humans due to similar anatomy and physiology....
2.
Nethi S, Kothadiya S, White B, Rachagani S, Bardhan R, Mallapragada S
ACS Appl Mater Interfaces . 2024 Dec; 16(51):70362-70377. PMID: 39666980
The heterogeneity of tumors and the lack of effective therapies have resulted in triple-negative breast cancer (TNBC) exhibiting the least favorable outcomes among breast cancer subtypes. TNBC is characterized by...
3.
Arciga B, Walters D, Kimchi E, Staveley-OCarroll K, Li G, Teixeiro E, et al.
Cancer Lett . 2024 Nov; 609:217361. PMID: 39608443
Cancer ablation with pulsed electric fields (PEFs) involves the delivery of high-voltage, short-duration electrical pulses that destabilize tumor cells, leading to cellular death. Unlike most conventional ablation technologies, PEF ablation...
4.
Joshi K, Suvilesh K, Natesh N, Manjunath Y, Coberly J, Schlink S, et al.
bioRxiv . 2024 Nov; PMID: 39569144
Background: There remains a need for animal models with human translatability in lung cancer (LC) research. Findings in pigs have high impact on humans due to similar anatomy and physiology....
5.
Ramos-Gonzalez M, Natesh N, Rachagani S, Amos-Landgraf J, Shirwan H, Yolcu E, et al.
Int J Mol Sci . 2024 Oct; 25(19). PMID: 39408747
Luciferase (luc) bioluminescence (BL) is the most used light-emitting protein that has been engineered to be expressed in multiple cancer cell lines, allowing for the detection of tumor nodules in...
6.
Kalbfleisch T, McKay S, Murdoch B, Adelson D, Almansa-Villa D, Becker G, et al.
Nat Genet . 2024 Aug; 56(8):1566-1573. PMID: 39103649
Telomere-to-telomere (T2T) assemblies reveal new insights into the structure and function of the previously 'invisible' parts of the genome and allow comparative analyses of complete genomes across entire clades. We...
7.
Suvilesh K, Manjunath Y, Nussbaum Y, Gadelkarim M, Raju M, Srivastava A, et al.
Clin Cancer Res . 2024 Jul; 30(17):3855-3867. PMID: 39017606
Purpose: Systemic treatments given to patients with non-small cell lung cancer (NSCLC) are often ineffective due to drug resistance. In the present study, we investigated patient-derived tumor organoids (PDTO) and...
8.
Joshi K, Katam T, Hegde A, Cheng J, Prather R, Whitworth K, et al.
World J Oncol . 2024 Mar; 15(2):149-168. PMID: 38545477
Pigs are playing an increasingly vital role as translational biomedical models for studying human pathophysiology. The annotation of the pig genome was a huge step forward in translatability of pigs...
9.
Atri P, Shah A, Natarajan G, Rachagani S, Rauth S, Ganguly K, et al.
NPJ Precis Oncol . 2024 Mar; 8(1):66. PMID: 38454151
Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to limited therapeutic options and expensive/burdensome drug discovery processes. Utilizing genomic-data-driven Connectivity Mapping (CMAP) to identify a drug closer to real-world PC...
10.
Joshi K, Telugu B, Prather R, Bryan J, Hoffman T, Kaifi J, et al.
Trends Cancer . 2024 Jan; 10(3):182-184. PMID: 38290969
Cancer remains a leading cause of morbidity and mortality, and a paradigm shift is needed to fundamentally revisit drug development efforts. Pigs share close similarities to humans and may serve...