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Sarah Neidler

Explore the profile of Sarah Neidler including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 278
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Recent Articles
1.
Muthalagu N, Monteverde T, Raffo-Iraolagoitia X, Wiesheu R, Whyte D, Hedley A, et al.
Cancer Discov . 2020 Mar; 10(6):872-887. PMID: 32200350
MYC is implicated in the development and progression of pancreatic cancer, yet the precise level of MYC deregulation required to contribute to tumor development has been difficult to define. We...
2.
Neidler S, Kruspig B, Hewit K, Monteverde T, Gyuraszova K, Braun A, et al.
Cancers (Basel) . 2019 Apr; 11(5). PMID: 31032816
Inducible genetically defined mouse models of cancer uniquely facilitate the investigation of early events in cancer progression, however, there are valid concerns about the ability of such models to faithfully...
3.
Kruspig B, Monteverde T, Neidler S, Hock A, Kerr E, Nixon C, et al.
Sci Transl Med . 2018 Jun; 10(446). PMID: 29925636
KRAS is the most frequently mutated driver oncogene in human adenocarcinoma of the lung. There are presently no clinically proven strategies for treatment of KRAS-driven lung cancer. Activating mutations in...
4.
Bott A, Peng I, Fan Y, Faubert B, Zhao L, Li J, et al.
Cell Metab . 2015 Nov; 22(6):1068-77. PMID: 26603296
c-Myc is known to promote glutamine usage by upregulating glutaminase (GLS), which converts glutamine to glutamate that is catabolized in the TCA cycle. Here we report that in a number...