Sara Sadat Aghamiri
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Explore the profile of Sara Sadat Aghamiri including associated specialties, affiliations and a list of published articles.
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11
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94
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Recent Articles
1.
Aghamiri S, Amin R
Discov Med
. 2025 Jan;
37(192):166-181.
PMID: 39851232
Background: Glioblastoma multiforme (GBM) is one of the deadliest and most heterogeneous forms of brain cancer, characterized by its resistance to conventional therapies. Within GBM, a subpopulation of slow-cycling cells,...
2.
Isavand P, Aghamiri S, Amin R
Biomedicines
. 2024 Aug;
12(8).
PMID: 39200217
Given advancements in large-scale data and AI, integrating multimodal artificial intelligence into cancer research can enhance our understanding of tumor behavior by simultaneously processing diverse biomedical data types. In this...
3.
Niarakis A, Ostaszewski M, Mazein A, Kuperstein I, Kutmon M, Gillespie M, et al.
Front Immunol
. 2024 Feb;
14:1282859.
PMID: 38414974
Introduction: The COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop...
4.
Veyssiere M, Aghamiri S, Hernandez Cervantes A, Henry T, Soumelis V
Clin Immunol
. 2023 Nov;
257:109839.
PMID: 37952562
Background: Familial Mediterranean Fever (FMF) is a monogenic disease caused by gain-of-function mutations in the MEditerranean FeVer (MEFV) gene. The molecular dysregulations induced by these mutations and the associated causal...
5.
Bessell B, Loecker J, Zhao Z, Aghamiri S, Mohanty S, Amin R, et al.
Brief Bioinform
. 2023 Nov;
24(6).
PMID: 37930022
Identifying potential drug targets using metabolic modeling requires integrating multiple modeling methods and heterogeneous biological datasets, which can be challenging without efficient tools. We developed Constraint-based Optimization of Metabolic Objectives...
6.
McMahon-Cole H, Johnson A, Aghamiri S, Helikar T, Crawford L
Curr Clin Microbiol Rep
. 2023 Oct;
10(3):141-151.
PMID: 37901689
Purpose Of Review: Human cytomegalovirus (HCMV), while asymptomatic in most, causes significant complications during fetal development, following transplant or in immunosuppressed individuals. The host-virus interactions regulating viral latency and reactivation...
7.
Aghamiri S, Puniya B, Amin R, Helikar T
Front Immunol
. 2023 Mar;
14:1112985.
PMID: 36993954
Dendritic cells (DCs) are professional antigen-presenting cells (APCs) with the unique ability to mediate inflammatory responses of the immune system. Given the critical role of DCs in shaping immunity, they...
8.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol
. 2021 Dec;
17(12):e10851.
PMID: 34939300
No abstract available.
9.
Recent applications of quantitative systems pharmacology and machine learning models across diseases
Aghamiri S, Amin R, Helikar T
J Pharmacokinet Pharmacodyn
. 2021 Oct;
49(1):19-37.
PMID: 34671863
Quantitative systems pharmacology (QSP) is a quantitative and mechanistic platform describing the phenotypic interaction between drugs, biological networks, and disease conditions to predict optimal therapeutic response. In this meta-analysis study,...
10.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol
. 2021 Oct;
17(10):e10387.
PMID: 34664389
We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here,...