Anna Niarakis
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Explore the profile of Anna Niarakis including associated specialties, affiliations and a list of published articles.
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37
Citations
493
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Recent Articles
1.
Sauro H, Agmon E, Blinov M, Gennari J, Hellerstein J, Heydarabadipour A, et al.
ArXiv
. 2025 Mar;
PMID: 40034129
Guidelines for managing scientific data have been established under the FAIR principles requiring that data be Findable, Accessible, Interoperable, and Reusable. In many scientific disciplines, especially computational biology, both data...
2.
Zerrouk N, Auge F, Niarakis A
NPJ Digit Med
. 2024 Dec;
7(1):379.
PMID: 39719524
Rheumatoid arthritis is a complex disease marked by joint pain, stiffness, swelling, and chronic synovitis, arising from the dysregulated interaction between synoviocytes and immune cells. Its unclear etiology makes finding...
3.
Niarakis A, Laubenbacher R, An G, Ilan Y, Fisher J, Flobak A, et al.
NPJ Syst Biol Appl
. 2024 Nov;
10(1):141.
PMID: 39616158
Digital twins represent a key technology for precision health. Medical digital twins consist of computational models that represent the health state of individual patients over time, enabling optimal therapeutics and...
4.
Niarakis A, Ostaszewski M, Mazein A, Kuperstein I, Kutmon M, Gillespie M, et al.
Front Immunol
. 2024 Feb;
14:1282859.
PMID: 38414974
Introduction: The COVID-19 Disease Map project is a large-scale community effort uniting 277 scientists from 130 Institutions around the globe. We use high-quality, mechanistic content describing SARS-CoV-2-host interactions and develop...
5.
Aghakhani S, Niarakis A, Soliman S
J Integr Bioinform
. 2024 Feb;
21(1).
PMID: 38314776
Molecular interaction maps (MIMs) are static graphical representations depicting complex biochemical networks that can be formalized using one of the Systems Biology Graphical Notation languages. Regardless of their extensive coverage...
6.
Zerrouk N, Alcraft R, Hall B, Auge F, Niarakis A
NPJ Syst Biol Appl
. 2024 Jan;
10(1):10.
PMID: 38272919
Macrophages play an essential role in rheumatoid arthritis. Depending on their phenotype (M1 or M2), they can play a role in the initiation or resolution of inflammation. The M1/M2 ratio...
7.
Aghakhani S, E Silva-Saffar S, Soliman S, Niarakis A
Comput Struct Biotechnol J
. 2023 Sep;
21:4196-4206.
PMID: 37705596
Cancer-associated fibroblasts (CAFs) are amongst the key players of the tumor microenvironment (TME) and are involved in cancer initiation, progression, and resistance to therapy. They exhibit aggressive phenotypes affecting extracellular...
8.
Singh V, Naldi A, Soliman S, Niarakis A
NPJ Syst Biol Appl
. 2023 Jul;
9(1):33.
PMID: 37454172
Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology. However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in initiating and perpetuating destructive joint inflammation by...
9.
Mazein A, Acencio M, Balaur I, Rougny A, Welter D, Niarakis A, et al.
Front Bioinform
. 2023 Jul;
3:1197310.
PMID: 37426048
As a conceptual model of disease mechanisms, a disease map integrates available knowledge and is applied for data interpretation, predictions and hypothesis generation. It is possible to model disease mechanisms...
10.
Aghakhani S, Soliman S, Niarakis A
PLoS Comput Biol
. 2022 Dec;
18(12):e1010408.
PMID: 36508473
Rheumatoid Arthritis (RA) is an autoimmune disease characterized by a highly invasive pannus formation consisting mainly of Synovial Fibroblasts (RASFs). This pannus leads to cartilage, bone, and soft tissue destruction...