Sara L Manning
Overview
Explore the profile of Sara L Manning including associated specialties, affiliations and a list of published articles.
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12
Citations
230
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Recent Articles
1.
Rupani D, Thege F, Chandra V, Rajaei H, Cowan R, Wormann S, et al.
Development
. 2022 Dec;
150(2).
PMID: 36458554
Adenosine deaminase acting on RNA 1 (ADAR1) is an RNA-binding protein that deaminates adenosine (A) to inosine (I). A-to-I editing alters post-transcriptional RNA processing, making ADAR1 a crucial regulator of...
2.
Thege F, Rupani D, Barathi B, Manning S, Maitra A, Rhim A, et al.
Cancer Res
. 2022 Jun;
82(15):2761-2776.
PMID: 35666804
Significance: A streamlined platform for programmable CRISPR gene activation enables rapid evaluation and functional validation of putative oncogenes in vivo.
3.
Wormann S, Zhang A, Thege F, Cowan R, Rupani D, Wang R, et al.
Nat Cancer
. 2022 Feb;
2(12):1338-1356.
PMID: 35121902
Despite efforts in understanding its underlying mechanisms, the etiology of chromosomal instability (CIN) remains unclear for many tumor types. Here, we identify CIN initiation as a previously undescribed function for...
4.
Pratt E, Cowan R, Manning S, Qiao E, Cameron H, Schradle K, et al.
Anal Chem
. 2019 May;
91(12):7516-7523.
PMID: 31072097
Oncology research is increasingly incorporating molecular detection of circulating tumor DNA (ctDNA) as a tool for cancer surveillance and early detection. However, noninvasive monitoring of conditions with low tumor burden...
5.
Bontempo L, Manning S
Emerg Med Clin North Am
. 2018 Nov;
37(1):109-119.
PMID: 30454773
Tracheostomy is a common procedure for long-term airway management. Although the overall complication rate is greater than 50%, the incidence of serious complications is low. These serious complications can, however,...
6.
Effects of exercise on circulating tumor cells among patients with resected stage I-III colon cancer
Brown J, Rhim A, Manning S, Brennan L, Mansour A, Rustgi A, et al.
PLoS One
. 2018 Oct;
13(10):e0204875.
PMID: 30332430
Background: Physical activity is associated with a lower risk of disease recurrence among colon cancer patients. Circulating tumor cells (CTC) are prognostic of disease recurrence among stage I-III colon cancer...
7.
Farrell A, Joly M, Allen-Petersen B, Worth P, Lanciault C, Sauer D, et al.
Nat Commun
. 2017 Nov;
8(1):1728.
PMID: 29170413
Intratumoral phenotypic heterogeneity has been described in many tumor types, where it can contribute to drug resistance and disease recurrence. We analyzed ductal and neuroendocrine markers in pancreatic ductal adenocarcinoma,...
8.
Westrick R, Tomberg K, Siebert A, Zhu G, Winn M, Dobies S, et al.
Proc Natl Acad Sci U S A
. 2017 Aug;
114(36):9659-9664.
PMID: 28827327
Factor V Leiden ( ) is a common genetic risk factor for venous thromboembolism in humans. We conducted a sensitized -ethyl--nitrosourea (ENU) mutagenesis screen for dominant thrombosuppressor genes based on...
9.
Jamtgaard L, Manning S, Cohn B
Ann Emerg Med
. 2015 Aug;
67(4):458-9.
PMID: 26234193
No abstract available.
10.
Westrick R, Mohlke K, Korepta L, Yang A, Zhu G, Manning S, et al.
Proc Natl Acad Sci U S A
. 2010 Sep;
107(39):16904-9.
PMID: 20837540
In characterizing mice with targeted disruption of the SerpinB2 gene, we observed animals that were small at birth with delayed growth and decreased life expectancy. Although this phenotype cosegregated with...