A Programmable In Vivo CRISPR Activation Model Elucidates the Oncogenic and Immunosuppressive Functions of MYC in Lung Adenocarcinoma

Overview

Journal Cancer Res

Specialty Oncology

Date 2022 Jun 6

PMID 35666804

Authors

Fredrik I Thege

Dhwani N Rupani

Bhargavi Brahmendra Barathi

Sara L Manning

Anirban Maitra

Andrew D Rhim

Sonja M Wormann

Affiliations

Soon will be listed here.

Abstract

Significance: A streamlined platform for programmable CRISPR gene activation enables rapid evaluation and functional validation of putative oncogenes in vivo.

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