Sanne M van Neerven
Overview
Explore the profile of Sanne M van Neerven including associated specialties, affiliations and a list of published articles.
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25
Citations
359
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Recent Articles
1.
Schwarzmueller L, Adam R, Moreno L, Nijman L, Logiantara A, Eleonora S, et al.
Gut
. 2024 Nov;
74(4):571-585.
PMID: 39562049
Background: Aberrant Wnt pathway activation is a key driver of colorectal cancer (CRC) and is essential to sustain tumour growth and progression. Although the downstream protein-coding target genes of the...
2.
van Driel M, Linssen J, van Neerven S, Vermeulen L
Gut
. 2023 Oct;
72(12):2222-2223.
PMID: 37884353
No abstract available.
3.
van Driel M, Linssen J, Flanagan D, Vlahov N, Nijman L, de Groot N, et al.
Cell Mol Gastroenterol Hepatol
. 2023 Jun;
16(4):652-655.
PMID: 37364735
No abstract available.
4.
Ramadan R, Wouters V, van Neerven S, de Groot N, Garcia T, Muncan V, et al.
Biol Open
. 2022 Nov;
11(12).
PMID: 36350252
The rapid renewal of the epithelial gut lining is fuelled by stem cells that reside at the base of intestinal crypts. The signal transduction pathways and morphogens that regulate intestinal...
5.
van Neerven S, Smit W, van Driel M, Kakkar V, de Groot N, Nijman L, et al.
EMBO Mol Med
. 2022 Nov;
14(12):e16194.
PMID: 36321561
The majority of colorectal cancers (CRCs) present with early mutations in tumor suppressor gene APC. APC mutations result in oncogenic activation of the Wnt pathway, which is associated with hyperproliferation,...
6.
van Neerven S, Vermeulen L
Nat Rev Mol Cell Biol
. 2022 Sep;
24(3):221-236.
PMID: 36175766
Organ development and homeostasis involve dynamic interactions between individual cells that collectively regulate tissue architecture and function. To ensure the highest tissue fidelity, equally fit cell populations are continuously renewed...
7.
Dings M, Manoukian P, Waasdorp C, Quik J, Strijker M, Lodestijn S, et al.
Int J Cancer
. 2022 Sep;
152(3):511-523.
PMID: 36069222
Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma, the main cellular constituents of which are cancer-associated fibroblasts (CAFs). Stroma-targeting agents have been proposed to improve the poor outcome of...
8.
Linssen J, van Neerven S, Aelvoet A, Elbers C, Vermeulen L, Dekker E
BMC Gastroenterol
. 2022 Aug;
22(1):383.
PMID: 35962368
Background: Familial adenomatous polyposis (FAP) is a rare autosomal dominant disease characterized by germline mutations in the Adenomatous Polyposis Coli (APC) gene, resulting in the development of numerous colorectal adenomas....
9.
Komen J, van Neerven S, Bossink E, de Groot N, Nijman L, van den Berg A, et al.
Micromachines (Basel)
. 2022 May;
13(5).
PMID: 35630206
The cancer xenograft model in which human cancer cells are implanted in a mouse is one of the most used preclinical models to test the efficacy of novel cancer drugs....
10.
Ramadan R, van Driel M, Vermeulen L, van Neerven S
Trends Cancer
. 2022 Feb;
8(5):416-425.
PMID: 35153158
The relationship between intestinal stem cells (ISCs) and colorectal cancer (CRC) has been a topic of intense study. Uncovering stem cell dynamics in homeostasis and following acquisition of oncogenic mutations...