Sangam Rajak
Overview
Explore the profile of Sangam Rajak including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
322
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Recent Articles
21.
Daniel P, Dogra S, Rawat P, Choubey A, Khan A, Rajak S, et al.
J Biol Chem
. 2021 Apr;
296:100714.
PMID: 33930463
Overconsumption of sucrose and other sugars has been associated with nonalcoholic fatty liver disease (NAFLD). Reports suggest hepatic de novo lipogenesis (DNL) as an important contributor to and regulator of...
22.
Rajak S, Iannucci L, Zhou J, Anjum B, George N, Singh B, et al.
Front Cell Dev Biol
. 2020 Oct;
8:523550.
PMID: 33083385
The hepatic mevalonate (MVA) pathway, responsible for cholesterol biosynthesis, is a therapeutically important metabolic pathway in clinical medicine. Using an unbiased transcriptomics approach, we uncover a novel role of Unc-51...
23.
Raza S, Rajak S, Upadhyay A, Tewari A, Sinha R
Front Biosci (Landmark Ed)
. 2020 Oct;
26(2):206-237.
PMID: 33049668
Non-alcoholic fatty liver disease (NAFLD) is one the fastest emerging manifestations of the metabolic syndrome worldwide. Non-alcoholic steatohepatitis (NASH), the progressive form of NAFLD, may culminate into cirrhosis and hepatocellular...
24.
Rajak S, Raza S, Tewari A, Yadav S, Ghosh S, Yen P, et al.
Biochem Biophys Res Commun
. 2020 Sep;
532(4):570-575.
PMID: 32900486
Hepatocellular cancer (HCC) is one of the leading causes of mortality worldwide. Unfortunately, a limited choice of anti-cancer drugs is available for treatment, owing to their minimal efficacy and development...
25.
Rajak S, Hussain Y, Singh K, Tiwari S, Ahmad B, Bharti S, et al.
Sci Rep
. 2020 Jun;
10(1):9102.
PMID: 32499562
We determined the role of cellular fibronectin (CFN) containing the alternatively spliced extra domain A (FN-EDA) in causing insulin resistance (IR) through toll-like receptor 4 (TLR4). Circulating FN-EDA level was...
26.
Pal S, Porwal K, Rajak S, Sinha R, Chattopadhyay N
Biomed Pharmacother
. 2020 May;
127:110207.
PMID: 32422565
Anabolic therapies for osteoporosis including dietary polyphenols promote osteoblast function by influencing its energy metabolism. Among the dietary polyphenols, the beneficial skeletal effects of genistein (an isoflavone), kaempferol (a flavone),...
27.
Sinha R, Rajak S, Singh B, Yen P
Int J Mol Sci
. 2020 Apr;
21(7).
PMID: 32244266
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors which belong to the nuclear hormone receptor superfamily. They regulate key aspects of energy metabolism within cells. Recently, PPARα has been implicated...
28.
Raza S, Rajak S, Anjum B, Sinha R
Hepatoma Res
. 2019 Dec;
5:42.
PMID: 31867441
Non-alcoholic fatty liver disease (NAFLD) and its advanced complication, non-alcoholic steatohepatitis (NASH), have become leading causes of hepatocellular carcinoma (HCC) worldwide. In this review, we discuss the role of metabolic,...
29.
Upadhyay A, Anjum B, Godbole N, Rajak S, Shukla P, Tiwari S, et al.
Biochem Biophys Res Commun
. 2019 May;
514(2):415-421.
PMID: 31053302
Maternal nutrition has become a major public health concern over recent years and is a known predictor of adverse long-term metabolic derangement in offspring. Time-restricted feeding (TRF), wherein food consumption...