Sangam Rajak
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Explore the profile of Sangam Rajak including associated specialties, affiliations and a list of published articles.
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29
Citations
322
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Recent Articles
11.
Raza S, Rajak S, Srivastava J, Tewari A, Gupta P, Chakravarti B, et al.
Biochim Biophys Acta Mol Cell Res
. 2022 Sep;
1869(12):119355.
PMID: 36113664
Autophagy and telomere maintenance are two cellular survival processes that show a strong correlation during human ageing and cancer growth, however, their causal relationship remains unclear. In this study, using...
12.
Chakravarti B, Rajput S, Raza S, Rajak S, Tewari A, Gupta P, et al.
Biochim Biophys Acta Mol Basis Dis
. 2022 Jun;
1868(10):166455.
PMID: 35680107
Autophagy inhibition is currently considered a novel therapeutic strategy for cancer treatment. Lipoic acid (LA), a naturally occurring compound found in all prokaryotic and eukaryotic cells, inhibits breast cancer cell...
13.
Rajak S, Raza S, Sinha R
Front Cell Dev Biol
. 2022 Mar;
10:836021.
PMID: 35252196
Liver is the primary organ for energy metabolism and detoxification in the human body. Not surprisingly, a derangement in liver function leads to several metabolic diseases. Autophagy is a cellular...
14.
Raza S, Rajak S, Tewari A, Gupta P, Chattopadhyay N, Sinha R, et al.
Semin Cancer Biol
. 2022 Jan;
86(Pt 3):1105-1121.
PMID: 34979274
Chemokines are small secretory chemotactic cytokines that control the directed migration of immune cells. Chemokines are involved in both anti-and pro-tumorigenic immune responses. Accumulating evidence suggests that the balance between...
15.
Rajak S, Gupta P, Anjum B, Raza S, Tewari A, Ghosh S, et al.
Biochim Biophys Acta Mol Basis Dis
. 2021 Dec;
1868(4):166319.
PMID: 34954342
Non-alcoholic steatohepatitis (NASH) is a clinically important spectrum of non-alcoholic fatty liver disease (NAFLD) in humans. NASH is a stage of NAFLD progression wherein liver steatosis accompanies inflammation and pro-fibrotic...
16.
Pal S, Singh M, Porwal K, Rajak S, Das N, Rajput S, et al.
Eur J Pharmacol
. 2021 Nov;
913:174634.
PMID: 34785210
Previously, we established adiponectin receptors (AdipoRs) as osteoanabolic target. To discover small molecule agonists of AdipoRs, we studied apigenin and apigenin-6C-glucopyranose (isovitexin) that induced osteoblast differentiation. In-silico, in vitro and...
17.
Rajak S, Raza S, Tewari A, Sinha R
Dig Dis Sci
. 2021 Aug;
67(8):3497-3507.
PMID: 34383198
The liver is an organ of vital importance in the body; it is the center of metabolic activities and acts as the primary line of defense against toxic compounds. Exposure...
18.
Rajak S, Yen P, Sinha R
Autophagy
. 2021 Aug;
17(10):3269-3270.
PMID: 34382918
Hormone synthesis and secretion is a highly regulated process governed by metabolic cues. Although peptide hormone action is largely governed by the rate of its synthesis and secretion by endocrine...
19.
Rajak S, Xie S, Tewari A, Raza S, Wu Y, Bay B, et al.
Mol Metab
. 2021 Jul;
53:101286.
PMID: 34224916
Objective: Crinophagy is a secretory granule-specific autophagic process that regulates hormone content and secretion in endocrine cells. However, despite being one of the earliest described autophagic processes, its mechanism of...
20.
Raza S, Tewari A, Rajak S, Sinha R
Liver Res
. 2021 Jul;
5(2):62-71.
PMID: 34221537
The incidence of non-alcoholic fatty liver disease (NAFLD) is rising rapidly across the globe. NAFLD pathogenesis is largely driven by an imbalance in hepatic energy metabolism and at present, there...