Sandra Merscher
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Explore the profile of Sandra Merscher including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Kim J, Yang E, Molina David J, Cho S, Ficarella M, Pape N, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684843
Mitochondrial dysfunction is a critical factor in the pathogenesis of Alport syndrome (AS), contributing to podocyte injury and disease progression. Ezetimibe, a lipid-lowering drug, is known to inhibit cholesterol and...
2.
Ahmad A, Anis A, Shamroop K, Mallela S, Ansari S, Saba A, et al.
Int J Radiat Oncol Biol Phys
. 2024 Dec;
121(5):1271-1281.
PMID: 39667585
Purpose: Radiation nephropathy (RN) can be a significant late complication after radiation therapy (RT) for abdominal and paraspinal tumors. The mechanisms for the development of RN are thought to involve...
3.
Duara J, Torres M, Gurumani M, Molina David J, Njeim R, Kim J, et al.
Am J Physiol Renal Physiol
. 2024 Jul;
327(3):F340-F350.
PMID: 38961844
Chronic kidney disease (CKD) is associated with renal lipid dysmetabolism among a variety of other pathways. We recently demonstrated that oxysterol-binding protein-like 7 (OSBPL7) modulates the expression and function of...
4.
Tolerico M, Merscher S, Fornoni A
Cells
. 2024 Jun;
13(11).
PMID: 38891023
Podocyte health is vital for maintaining proper glomerular filtration in the kidney. Interdigitating foot processes from podocytes form slit diaphragms which regulate the filtration of molecules through size and charge...
5.
Ge M, Molina J, Tamayo I, Zhang G, Kim J, Njeim R, et al.
Kidney360
. 2024 May;
5(7):1002-1011.
PMID: 38781016
No abstract available.
6.
Njeim R, Merscher S, Fornoni A
Am J Physiol Renal Physiol
. 2024 Apr;
326(6):F877-F893.
PMID: 38601984
Autophagy is a protective mechanism through which cells degrade and recycle proteins and organelles to maintain cellular homeostasis and integrity. An accumulating body of evidence underscores the significant impact of...
7.
Burke G, Mitrofanova A, Fontanella A, Vendrame F, Ciancio G, Vianna R, et al.
Front Immunol
. 2024 Mar;
15:1354101.
PMID: 38495894
Beyond the direct benefit that a transplanted organ provides to an individual recipient, the study of the transplant process has the potential to create a better understanding of the pathogenesis,...
8.
Gipson D, Wang C, Salmon E, Gbadegesin R, Naik A, Sanna-Cherchi S, et al.
Glomerular Dis
. 2024 Feb;
4(1):1-10.
PMID: 38348154
No abstract available.
9.
Burke 3rd G, Mitrofanova A, Fontanella A, Ciancio G, Roth D, Ruiz P, et al.
Front Immunol
. 2023 Aug;
14:1201619.
PMID: 37564655
Focal segmental glomerulosclerosis (FSGS) is a common glomerular disorder that manifests clinically with the nephrotic syndrome and has a propensity to recur following kidney transplantation. The pathophysiology and therapies available...
10.
Mitrofanova A, Merscher S, Fornoni A
Nat Rev Nephrol
. 2023 Jul;
19(10):629-645.
PMID: 37500941
Chronic kidney disease (CKD) is a global health problem with rising incidence and prevalence. Among several pathogenetic mechanisms responsible for disease progression, lipid accumulation in the kidney parenchyma might drive...