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Sandra J van Vliet

Explore the profile of Sandra J van Vliet including associated specialties, affiliations and a list of published articles. Areas
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Articles 102
Citations 3886
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Recent Articles
11.
van Spronsen M, Horrevorts S, Cali C, Westers T, Van Gassen S, Saeys Y, et al.
Leukemia . 2023 Feb; 37(3):702-707. PMID: 36759685
No abstract available.
12.
da Costa V, Marino K, Rodriguez-Zraquia S, Festari M, Lores P, Costa M, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36233358
Lung cancer is the first leading cause of cancer-related deaths in the world. Aberrant glycosylation in lung tumors leads to the expression of tumor-associated carbohydrate structures, such as the Tn...
13.
Lubbers J, Eveline Li R, Gorki F, Bruijns S, Gallagher A, Kalay H, et al.
Immunother Adv . 2022 Aug; 1(1):ltab012. PMID: 35919745
Objective: We here investigated whether α2-3sia, that bind immune inhibitory Siglec receptors, would alter signaling and reprogramming of LPS-stimulated human monocyte-derived DCs (moDCs). Methods And Results: Transcriptomic analysis of moDCs...
14.
Rodriguez E, Boelaars K, Brown K, Madunic K, van Ee T, Dijk F, et al.
Commun Biol . 2022 Jan; 5(1):41. PMID: 35017635
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive malignancies with a 5-year survival rate of only 9%. Despite the fact that changes in glycosylation patterns during tumour progression...
15.
da Costa V, van Vliet S, Carasi P, Frigerio S, Garcia P, Croci D, et al.
Cancer Lett . 2021 Jun; 518:72-81. PMID: 34144098
Tn is a tumor-associated carbohydrate antigen that constitutes both a diagnostic tool and an immunotherapeutic target. It originates from interruption of the mucin O-glycosylation pathway through defects involving, at least...
16.
Stolk D, Horrevorts S, Schetters S, Kruijssen L, Duinkerken S, Keuning E, et al.
Mol Ther Oncolytics . 2021 Jun; 21:315-328. PMID: 34141869
Induction of tumor-specific cytotoxic CD8 T cells (CTLs) via immunization relies on the presentation of tumor-associated peptides in major histocompatibility complex (MHC) class I molecules by dendritic cells (DCs). To...
17.
Eveline Li R, de Haas A, Rodriguez E, Kalay H, Zaal A, Jimenez C, et al.
Front Immunol . 2021 May; 12:673454. PMID: 33968084
Dendritic cells (DCs) are key initiators of the adaptive immunity, and upon recognition of pathogens are able to skew T cell differentiation to elicit appropriate responses. DCs possess this extraordinary...
18.
Anderluh M, Berti F, Bzducha-Wrobel A, Chiodo F, Colombo C, Compostella F, et al.
FEBS J . 2021 May; 289(14):4251-4303. PMID: 33934527
Vaccination is one of the greatest achievements in biomedical research preventing death and morbidity in many infectious diseases through the induction of pathogen-specific humoral and cellular immune responses. Currently, no...
19.
Anderluh M, Berti F, Bzducha-Wrobel A, Chiodo F, Colombo C, Compostella F, et al.
FEBS J . 2021 Mar; 288(16):4746-4772. PMID: 33752265
Glycan structures are common posttranslational modifications of proteins, which serve multiple important structural roles (for instance in protein folding), but also are crucial participants in cell-cell communications and in the...
20.
Rodriguez E, Boelaars K, Brown K, Li R, Kruijssen L, Bruijns S, et al.
Nat Commun . 2021 Feb; 12(1):1270. PMID: 33627655
Changes in glycosylation during tumour progression are a key hallmark of cancer. One of the glycan moieties generally overexpressed in cancer are sialic acids, which can induce immunomodulatory properties via...