Sandra J van Vliet
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Explore the profile of Sandra J van Vliet including associated specialties, affiliations and a list of published articles.
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102
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3886
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Recent Articles
1.
Asal M, Thon M, Waaijman T, Bontkes H, van Vliet S, Mebius R, et al.
Biomedicines
. 2025 Jan;
12(12.
PMID: 39767819
: The barrier properties of the human small intestine play a crucial role in regulating digestion, nutrient absorption and drug metabolism. Current in vitro organotypic models consist only of an...
2.
van der Meijs N, Travecedo M, Marcelo F, van Vliet S
Expert Opin Ther Targets
. 2024 Jul;
28(7):601-612.
PMID: 38946482
Introduction: CLEC10A is a C-type lectin receptor that specifically marks the conventional dendritic cell subsets two and three (cDC2 and DC3). It has a unique recognition profile of glycan antigens,...
3.
van der Haar Avila I, Zhang T, Lorrain V, de Bruin F, Spreij T, Nakayama H, et al.
Glycobiology
. 2024 May;
34(7).
PMID: 38785323
Aberrant glycosylation is a key mechanism employed by cancer cells to evade immune surveillance, induce angiogenesis and metastasis, among other hallmarks of cancer. Sialic acids, distinctive terminal glycan structures located...
4.
Boelaars K, Rodriguez E, Huinen Z, Liu C, Wang D, Springer B, et al.
Commun Biol
. 2024 Apr;
7(1):430.
PMID: 38594506
Despite recent advances in cancer immunotherapy, pancreatic ductal adenocarcinoma (PDAC) remains unresponsive due to an immunosuppressive tumor microenvironment, which is characterized by the abundance of cancer-associated fibroblasts (CAFs). Once identified,...
5.
Rodriguez E, Lindijer D, van Vliet S, Garcia Vallejo J, van Kooyk Y
iScience
. 2024 Feb;
27(3):109037.
PMID: 38384845
Changes in glycosylation patterns have been associated with malignant transformation and clinical outcomes in several cancer types, prompting ongoing research into the mechanisms involved and potential clinical applications. In this...
6.
Keumatio Doungtsop B, Nardini E, Kalay H, Versteeg S, Lubbers J, van Barneveld G, et al.
J Allergy Clin Immunol Glob
. 2024 Jan;
3(1):100193.
PMID: 38187864
Background: House dust mite extract-based allergen immunotherapy (AIT) to treat house dust mite allergy is substantially effective but still presents some safety and efficacy concerns that warrant improvement. Several major...
7.
Asal M, Rep M, Bontkes H, van Vliet S, Mebius R, Gibbs S
Tissue Eng Regen Med
. 2023 Dec;
21(3):369-377.
PMID: 38113015
Introduction: Since small intestine is one of the major barriers of the human body, there is a need to develop reliable in vitro human small intestinal models. These models should...
8.
Boelaars K, Goossens-Kruijssen L, Wang D, de Winde C, Rodriguez E, Lindijer D, et al.
J Immunother Cancer
. 2023 Nov;
11(11).
PMID: 37940346
Background: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Despite the successful application of immune checkpoint blockade in a range of human cancers, immunotherapy in PDAC remains unsuccessful....
9.
Gabba A, Attariya R, Behren S, Pett C, van der Horst J, Yurugi H, et al.
J Am Chem Soc
. 2023 Jun;
145(24):13027-13037.
PMID: 37279388
Mucin expression and glycosylation patterns on cancer cells differ markedly from healthy cells. Mucin 1 (MUC1) is overexpressed in several solid tumors and presents high levels of aberrant, truncated O-glycans...
10.
van der Haar Avila I, Windhouwer B, van Vliet S
Cancer Metastasis Rev
. 2023 Jun;
42(3):941-958.
PMID: 37266839
Gangliosides are sialylated glycolipids, mainly present at the cell surface membrane, involved in a variety of cellular signaling events. During malignant transformation, the composition of these glycosphingolipids is altered, leading...