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Sandor Farkas

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Articles 36
Citations 186
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Recent Articles
1.
Sipos T, Orsi-Gibicsar S, Schieszl T, Donko T, Zakk Z, Farkas S, et al.
Insects . 2024 Sep; 15(9). PMID: 39336662
The is the most significant bee parasite and the greatest threat to bee health all around the world. Due to its hidden lifestyle, detection within the brood cell is only...
2.
Mohos V, Harmat M, Kun J, Aczel T, Zsido B, Kitka T, et al.
Front Pharmacol . 2024 Sep; 15:1461355. PMID: 39221150
Chronic orofacial pain disorders are common debilitating conditions, affecting the trigeminal system. Its underlying pathophysiological mechanisms are still unclear and the therapy is often unsatisfactory, therefore, preclinical models are crucial...
3.
Benedekovic G, Farkas S, Popsavin M, Stanisavljevic S, Djokic S, Francuz J, et al.
Bioorg Med Chem . 2024 Jul; 111:117848. PMID: 39067378
A new total synthesis of the natural δ-lactone cleistenolide (1) and its (6S)-stereoisomer 2 was achieved starting from d-glucose. Key steps in the synthesis of 1 involved: oxidative cleavage of...
4.
Szeker P, Bodo T, Klima K, Csoti A, Hanh N, Muranyi J, et al.
J Biol Chem . 2024 Mar; 300(4):107155. PMID: 38479597
Despite significant advances in the development of therapeutic interventions targeting autoimmune diseases and chronic inflammatory conditions, lack of effective treatment still poses a high unmet need. Modulating chronically activated T...
5.
Farkas S, Cioca D, Muranyi J, Hornyak P, Brunyanszki A, Szeker P, et al.
J Biol Chem . 2023 Jul; 299(9):104998. PMID: 37394009
Chlorotoxin (CTX), a scorpion venom-derived 36-residue miniprotein, binds to and is taken up selectively by glioblastoma cells. Previous studies provided controversial results concerning target protein(s) of CTX. These included CLC3...
6.
Benedekovic G, Popsavin M, Radulovic N, Stojanovic-Radic Z, Farkas S, Francuz J, et al.
Bioorg Chem . 2020 Dec; 106:104491. PMID: 33268006
Using the "chiral pool" approach, two modified total syntheses of the biologically active δ-lactone cleistenolide (1) have been achieved starting from d-glucose. These approaches also enabled the preparation of novel...
7.
Deres L, Eros K, Horvath O, Bencze N, Cseko C, Farkas S, et al.
Front Physiol . 2019 Jun; 10:624. PMID: 31178756
It is known that non-steroidal anti-inflammatory drugs increase cardiovascular (CV) morbidity and mortality. In this study, we examined whether a novel anti-inflammatory drug, bradykinin B1 receptor antagonist (FGY-1153) treatment could...
8.
Hajna Z, Szabadfi K, Balla Z, Biro Z, Degrell P, Molnar G, et al.
J Pharmacol Toxicol Methods . 2015 Nov; 78:1-12. PMID: 26589430
Introduction: Accurate preclinical modeling of diabetic complications such as retinopathy, nephropathy and neuropathy is crucial to enable the development of novel preventative therapies. The aims of this study were to...
9.
Farkas S, Bolcskei K, Markovics A, Varga A, Kis-Varga A, Kormos V, et al.
J Pharmacol Toxicol Methods . 2015 Oct; 77:33-44. PMID: 26456070
Introduction: Majority of the work for establishing nitroglycerin (NTG)-induced migraine models in animals was done in rats, though recently some studies in mice were also reported. Different special formulations of...
10.
Farkas B, Kardos P, Orosz S, Tarnawa I, Cseko C, Levay G, et al.
Brain Res . 2015 Sep; 1625:287-300. PMID: 26358146
The trigeminovascular system has a pivotal role in the pathomechanism of migraine. The aim of the present study was to further develop existing models of migraine making them more suitable...