Sander R Piersma
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Explore the profile of Sander R Piersma including associated specialties, affiliations and a list of published articles.
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144
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3456
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Recent Articles
11.
Gali A, Bijnsdorp I, Piersma S, Pham T, Gutierrez-Galindo E, Kuhnel F, et al.
iScience
. 2024 Feb;
27(2):108958.
PMID: 38323010
The protein kinase D (PKD) family members regulate the fission of cargo vesicles at the Golgi complex and play a pro-oncogenic role in triple-negative breast cancer (TNBC). Whether PKD facilitates...
12.
Almeida-Marques C, Rolfs F, Piersma S, Bijnsdorp I, Pham T, Knol J, et al.
Proteomics
. 2024 Jan;
24(7):e2300262.
PMID: 38221716
The cancer cell secretome comprises a treasure-trove for biomarkers since it reflects cross-talk between tumor cells and their surrounding environment with high detectability in biofluids. In this study, we evaluated...
13.
Bottger F, Radonic T, Bahce I, Monkhorst K, Piersma S, Pham T, et al.
Mol Oncol
. 2023 Nov;
18(6):1417-1436.
PMID: 38010703
The majority of patients with resected stage II-IIIA non-small cell lung cancer (NSCLC) are treated with platinum-based adjuvant chemotherapy (ACT) in a one-size-fits-all approach. However, a significant number of patients...
14.
van der Wijngaart H, Beekhof R, Knol J, Henneman A, de Goeij-de Haas R, Piersma S, et al.
Clin Proteomics
. 2023 Nov;
20(1):49.
PMID: 37940875
The tyrosine kinase inhibitor sunitinib is an effective first-line treatment for patients with advanced renal cell carcinoma (RCC). Hypothesizing that a functional read-out by mass spectrometry-based (phospho, p-)proteomics will identify...
15.
Rolfs F, de Goeij-de Haas R, Knol J, Piersma S, Jimenez C
Methods Mol Biol
. 2023 Sep;
2718:285-302.
PMID: 37665466
Proteogenomic analysis is emerging as an advantageous tool to assist personalized therapy decisions in clinical health care and integrates complementary information from the genome, transcriptome, and (phospho)proteome. A prerequisite for...
16.
Erozenci L, Bijnsdorp I, Piersma S, Jimenez C
Methods Mol Biol
. 2023 Sep;
2718:235-251.
PMID: 37665463
Urinary extracellular vesicles (uEVs) are a rich source of noninvasive protein biomarkers. However, for translation to clinical applications, an easy-to-use uEV isolation protocol is needed that is compatible with proteomics....
17.
Beekhof R, Bertotti A, Bottger F, Vurchio V, Cottino F, Zanella E, et al.
Sci Transl Med
. 2023 Aug;
15(709):eabm3687.
PMID: 37585503
Epidermal growth factor receptor (EGFR) is a well-exploited therapeutic target in metastatic colorectal cancer (mCRC). Unfortunately, not all patients benefit from current EGFR inhibitors. Mass spectrometry-based proteomics and phosphoproteomics were...
18.
Xue Z, Zhu T, Zhang F, Zhang C, Xiang N, Qian L, et al.
Patterns (N Y)
. 2023 Jul;
4(7):100792.
PMID: 37521047
A comprehensive pan-human spectral library is critical for biomarker discovery using mass spectrometry (MS)-based proteomics. DPHL v.1, a previous pan-human library built from 1,096 data-dependent acquisition (DDA) MS data of...
19.
Algul S, Schuldt M, Manders E, Jansen V, Schlossarek S, de Goeij-de Haas R, et al.
Circ Res
. 2023 Jul;
133(5):387-399.
PMID: 37477020
Background: Diastolic dysfunction is central to diseases such as heart failure with preserved ejection fraction and hypertrophic cardiomyopathy (HCM). However, therapies that improve cardiac relaxation are scarce, partly due to...
20.
Paciotti S, Wojdala A, Bellomo G, Toja A, Chipi E, Piersma S, et al.
Alzheimers Res Ther
. 2023 Jul;
15(1):124.
PMID: 37454217
Background: Alzheimer's disease (AD) cerebrospinal fluid (CSF) core biomarkers (Aβ42/40 ratio, p-tau, and t-tau) provide high diagnostic accuracy, even at the earliest stage of disease. However, these markers do not...