Samuel W Lukowski
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Explore the profile of Samuel W Lukowski including associated specialties, affiliations and a list of published articles.
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36
Citations
1073
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Recent Articles
1.
Shen S, Werner T, Lukowski S, Andersen S, Sun Y, Shim W, et al.
Nat Commun
. 2025 Feb;
16(1):1356.
PMID: 39904980
Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across developmental lineages. Here, we engineer barcoded induced pluripotent stem cells to generate an atlas of...
2.
Stary V, Pandey R, List J, Kleissl L, Deckert F, Kabiljo J, et al.
Nat Commun
. 2024 Aug;
15(1):6949.
PMID: 39138181
Although γδ T cells are known to participate in immune dysregulation in solid tumors, their relevance to human microsatellite-stable (MSS) colorectal cancer (CRC) is still undefined. Here, using integrated gene...
3.
Shamanskiy V, Mikhailova A, Tretiakov E, Ushakova K, Mikhailova A, Oreshkov S, et al.
BMC Biol
. 2023 May;
21(1):103.
PMID: 37158879
Background: Aging in postmitotic tissues is associated with clonal expansion of somatic mitochondrial deletions, the origin of which is not well understood. Such deletions are often flanked by direct nucleotide...
4.
McKinnon B, Lukowski S, Mortlock S, Crawford J, Atluri S, Subramaniam S, et al.
Commun Biol
. 2022 Jun;
5(1):600.
PMID: 35725766
Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium is a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibroblasts...
5.
Krueger A, Zaugg J, Chisholm S, Linedale R, Lachner N, Teoh S, et al.
Front Microbiol
. 2022 Feb;
12:789042.
PMID: 35145494
Squamous cell carcinoma (SCC) is a common type of skin cancer that typically arises from premalignant precursor lesions named actinic keratoses (AK). Chronic inflammation is a well-known promoter of skin...
6.
Tuong Z, Lukowski S, Nguyen Q, Chandra J, Zhou C, Gillinder K, et al.
iScience
. 2021 Nov;
24(11):103326.
PMID: 34805788
Langerhans cells (LC) are skin-resident antigen-presenting cells that regulate immune responses to epithelial microorganisms. Human papillomavirus (HPV) infection can promote malignant epithelial transformation. As LCs are considered important for controlling...
7.
Rodahl I, Gotley J, Andersen S, Yu M, Mehdi A, Christ A, et al.
STAR Protoc
. 2021 Sep;
2(4):100842.
PMID: 34585169
Here, we outline detailed protocols to isolate and profile murine splenic dendritic cells (DCs) through advanced flow cytometry of the myeloid compartment and single-cell transcriptomic profiling with integrated cell surface...
8.
Lukowski S, Rodahl I, Kelly S, Yu M, Gotley J, Zhou C, et al.
iScience
. 2021 May;
24(5):102402.
PMID: 33997687
Conventional dendritic cells (cDCs) are traditionally subdivided into cDC1 and cDC2 lineages. Batf3 is a cDC1-required transcription factor, and we observed that -/- mice harbor a population of cDC1-like cells...
9.
Neavin D, Nguyen Q, Daniszewski M, Liang H, Chiu H, Wee Y, et al.
Genome Biol
. 2021 Mar;
22(1):76.
PMID: 33673841
Background: The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) has provided a foundation for in vitro human disease modelling, drug development and population genetics...
10.
Comparative performance of the BGI and Illumina sequencing technology for single-cell RNA-sequencing
Senabouth A, Andersen S, Shi Q, Shi L, Jiang F, Zhang W, et al.
NAR Genom Bioinform
. 2021 Feb;
2(2):lqaa034.
PMID: 33575589
The libraries generated by high-throughput single cell RNA-sequencing (scRNA-seq) platforms such as the Chromium from 10× Genomics require considerable amounts of sequencing, typically due to the large number of cells....