Anne Senabouth
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Explore the profile of Anne Senabouth including associated specialties, affiliations and a list of published articles.
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22
Citations
845
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Recent Articles
1.
Neavin D, Senabouth A, Arora H, Lee J, Ripoll-Cladellas A, Franke L, et al.
Genome Biol
. 2024 Apr;
25(1):94.
PMID: 38622708
Recent innovations in single-cell RNA-sequencing (scRNA-seq) provide the technology to investigate biological questions at cellular resolution. Pooling cells from multiple individuals has become a common strategy, and droplets can subsequently...
2.
Greatbatch C, Lu Q, Hung S, Barnett A, Wing K, Liang H, et al.
Hum Mol Genet
. 2024 Jan;
33(9):739-751.
PMID: 38272457
Introduction: Primary open angle glaucoma (POAG) is a leading cause of blindness globally. Characterized by progressive retinal ganglion cell degeneration, the precise pathogenesis remains unknown. Genome-wide association studies (GWAS) have...
3.
Grimm L, Mason E, Yu H, Dudczig S, Panara V, Chen T, et al.
EMBO J
. 2023 Mar;
42(11):e112590.
PMID: 36912146
During development, the lymphatic vasculature forms as a second network derived chiefly from blood vessels. The transdifferentiation of embryonic venous endothelial cells (VECs) into lymphatic endothelial cells (LECs) is a...
4.
Daniszewski M, Senabouth A, Liang H, Han X, Lidgerwood G, Hernandez D, et al.
Cell Genom
. 2023 Feb;
2(6):100142.
PMID: 36778138
To assess the transcriptomic profile of disease-specific cell populations, fibroblasts from patients with primary open-angle glaucoma (POAG) were reprogrammed into induced pluripotent stem cells (iPSCs) before being differentiated into retinal...
5.
Senabouth A, Daniszewski M, Lidgerwood G, Liang H, Hernandez D, Mirzaei M, et al.
Nat Commun
. 2022 Jul;
13(1):4233.
PMID: 35882847
There are currently no treatments for geographic atrophy, the advanced form of age-related macular degeneration. Hence, innovative studies are needed to model this condition and prevent or delay its progression....
6.
Yazar S, Alquicira-Hernandez J, Wing K, Senabouth A, Gordon M, Andersen S, et al.
Science
. 2022 Apr;
376(6589):eabf3041.
PMID: 35389779
The human immune system displays substantial variation between individuals, leading to differences in susceptibility to autoimmune disease. We present single-cell RNA sequencing (scRNA-seq) data from 1,267,758 peripheral blood mononuclear cells...
7.
Currant H, Hysi P, Fitzgerald T, Gharahkhani P, Bonnemaijer P, Senabouth A, et al.
PLoS Genet
. 2021 Oct;
17(10):e1009858.
PMID: 34662343
[This corrects the article DOI: 10.1371/journal.pgen.1009497.].
8.
Thompson M, Matsumoto M, Ma T, Senabouth A, Palpant N, Powell J, et al.
Front Genet
. 2021 Aug;
12:666771.
PMID: 34349778
Finding cell states and their transcriptional relatedness is a main outcome from analysing single-cell data. In developmental biology, determining whether cells are related in a differentiation lineage remains a major...
9.
Cohen J, Blumenthal A, Cuellar-Partida G, Evans D, Finfer S, Li Q, et al.
Intensive Care Med
. 2021 Jun;
47(9):974-983.
PMID: 34185116
Purpose: To determine if adrenocortical gene expression is associated with clinical outcomes or response to corticosteroid treatment in septic shock. Methods: A pre-specified nested cohort study of a randomised controlled...
10.
Currant H, Hysi P, Fitzgerald T, Gharahkhani P, Bonnemaijer P, Senabouth A, et al.
PLoS Genet
. 2021 May;
17(5):e1009497.
PMID: 33979322
Optical Coherence Tomography (OCT) enables non-invasive imaging of the retina and is used to diagnose and manage ophthalmic diseases including glaucoma. We present the first large-scale genome-wide association study of...