Samuel W Lukowski
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Explore the profile of Samuel W Lukowski including associated specialties, affiliations and a list of published articles.
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36
Citations
1073
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Recent Articles
11.
Vilar R, Lukowski S, Garieri M, Di Sanza C, Neerman-Arbez M, Fish R
Thromb Haemost
. 2020 Dec;
121(4):433-448.
PMID: 33302304
Thrombosis is a leading cause of morbidity and mortality. Fibrinogen, the soluble substrate for fibrin-based clotting, has a central role in haemostasis and thrombosis and its plasma concentration correlates with...
12.
Budhwani M, Lukowski S, Porceddu S, Frazer I, Chandra J
Front Cell Infect Microbiol
. 2020 Jul;
10:307.
PMID: 32670895
Human papillomavirus (HPV) infection is associated with a range of malignancies that affect anogenital and oropharyngeal sites. α-HPVs dominantly infect basal epithelial cells of mucosal tissues, where they dysregulate cell...
13.
Mortlock S, Kendarsari R, Fung J, Gibson G, Yang F, Restuadi R, et al.
Hum Reprod
. 2020 Feb;
35(2):377-393.
PMID: 32103259
Study Question: Are genetic effects on endometrial gene expression tissue specific and/or associated with reproductive traits and diseases? Summary Answer: Analyses of RNA-sequence data and individual genotype data from the...
14.
Byrne A, Powell J, OSullivan B, Ogger P, Hoffland A, Cook J, et al.
J Exp Med
. 2020 Jan;
217(3).
PMID: 31917836
The ontogeny of airway macrophages (AMs) in human lung and their contribution to disease are poorly mapped out. In mice, aging is associated with an increasing proportion of peripherally, as...
15.
Senabouth A, Lukowski S, Hernandez J, Andersen S, Mei X, Nguyen Q, et al.
Gigascience
. 2019 Sep;
8(8).
PMID: 31505654
Background: Recent developments in single-cell RNA sequencing (scRNA-seq) platforms have vastly increased the number of cells typically assayed in an experiment. Analysis of scRNA-seq data is multidisciplinary in nature, requiring...
16.
Lukowski S, Lo C, Sharov A, Nguyen Q, Fang L, Hung S, et al.
EMBO J
. 2019 Aug;
38(18):e100811.
PMID: 31436334
The retina is a specialized neural tissue that senses light and initiates image processing. Although the functional organization of specific retina cells has been well studied, the molecular profile of...
17.
Devitt K, Hanson S, Tuong Z, McMeniman E, Soyer H, Frazer I, et al.
Virology
. 2019 Aug;
537:14-19.
PMID: 31425970
Human Papillomavirus infection is highly prevalent worldwide. While most types of HPV cause benign warts, some high-risk types are known to cause cervical cancer, as well as cancer of the...
18.
Lukowski S, Patel J, Andersen S, Sim S, Wong H, Tay J, et al.
Cell Rep
. 2019 May;
27(9):2748-2758.e3.
PMID: 31141696
The cellular and molecular profiles that govern the endothelial heterogeneity of the circulatory system have yet to be elucidated. Using a data-driven approach to study the endothelial compartment via single-cell...
19.
Mortlock S, Restuadi R, Levien R, Girling J, Holdsworth-Carson S, Healey M, et al.
Clin Epigenetics
. 2019 Mar;
11(1):49.
PMID: 30871624
Background: Major challenges in understanding the functional consequences of genetic risk factors for human disease are which tissues and cell types are affected and the limited availability of suitable tissue....
20.
Friedman C, Nguyen Q, Lukowski S, Helfer A, Chiu H, Miklas J, et al.
Cell Stem Cell
. 2018 Oct;
23(4):586-598.e8.
PMID: 30290179
Cardiac differentiation of human pluripotent stem cells (hPSCs) requires orchestration of dynamic gene regulatory networks during stepwise fate transitions but often generates immature cell types that do not fully recapitulate...