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Samira Benhamouche

Explore the profile of Samira Benhamouche including associated specialties, affiliations and a list of published articles. Areas
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Articles 7
Citations 588
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Recent Articles
1.
Raymond A, Benhamouche S, Neaud V, Di Martino J, Javary J, Rosenbaum J
PLoS One . 2015 Apr; 10(4):e0123333. PMID: 25875766
Reptin/RUVBL2 is overexpressed in most hepatocellular carcinomas and is required for the growth and viability of HCC cells. Reptin is involved in several chromatin remodeling complexes, some of which are...
2.
Fitamant J, Kottakis F, Benhamouche S, Tian H, Chuvin N, Parachoniak C, et al.
Cell Rep . 2015 Mar; 10(10):1692-1707. PMID: 25772357
Defective Hippo/YAP signaling in the liver results in tissue overgrowth and development of hepatocellular carcinoma (HCC). Here, we uncover mechanisms of YAP-mediated hepatocyte reprogramming and HCC pathogenesis. YAP functions as...
3.
Torre C, Benhamouche S, Mitchell C, Godard C, Veber P, Letourneur F, et al.
J Hepatol . 2010 Dec; 55(1):86-95. PMID: 21145869
Background & Aims: β-Catenin is an oncogene frequently mutated in hepatocellular carcinoma. In this study, we investigated target genes of β-catenin signaling in hepatocyte proliferation. Methods: We studied transgenic mice...
4.
Benhamouche S, Curto M, Saotome I, Gladden A, Liu C, Giovannini M, et al.
Genes Dev . 2010 Aug; 24(16):1718-30. PMID: 20675406
The molecular signals that control the maintenance and activation of liver stem/progenitor cells are poorly understood, and the role of liver progenitor cells in hepatic tumorigenesis is unclear. We report...
5.
Cavard C, Colnot S, Audard V, Benhamouche S, Finzi L, Torre C, et al.
Future Oncol . 2008 Oct; 4(5):647-60. PMID: 18922122
The Wnt/beta-catenin pathway is a key developmental pathway for which alterations have been described in various human cancers. The aberrant activation of this pathway is a major event in human...
6.
Benhamouche S, Decaens T, Perret C, Colnot S
Med Sci (Paris) . 2006 Nov; 22(11):904-6. PMID: 17101081
No abstract available.
7.
Benhamouche S, Decaens T, Godard C, Chambrey R, Rickman D, Moinard C, et al.
Dev Cell . 2006 Jun; 10(6):759-70. PMID: 16740478
The molecular mechanisms by which liver genes are differentially expressed along a portocentral axis, allowing for metabolic zonation, are poorly understood. We provide here compelling evidence that the Wnt/beta-catenin pathway...