Helen S Tian
Overview
Explore the profile of Helen S Tian including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
245
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Recent Articles
1.
Williams R, Shah J, Mercer E, Tian H, Thompson V, Cheung J, et al.
Front Pharmacol
. 2022 Jan;
12:790913.
PMID: 35046813
Cisplatin-induced acute kidney injury (CI-AKI) is a significant co-morbidity of chemotherapeutic regimens. While this condition is associated with substantially lower survival and increased economic burden, there is no pharmacological agent...
2.
Kurth I, Yamaguchi N, Andreu-Agullo C, Tian H, Sridhar S, Takeda S, et al.
Sci Adv
. 2021 Oct;
7(41):eabi7511.
PMID: 34613776
Colorectal cancer (CRC) is a leading cause of cancer mortality. Creatine metabolism was previously shown to critically regulate colon cancer progression. We report that RGX-202, an oral small-molecule SLC6A8 transporter...
3.
Xiao W, Miles L, Bowman R, Durani V, Tian H, DelGaudio N, et al.
Blood Adv
. 2020 Dec;
4(23):6034-6038.
PMID: 33284943
No abstract available.
4.
Cai S, Chu S, Goldberg A, Parvin S, Koche R, Glass J, et al.
Cancer Discov
. 2020 Jul;
10(10):1500-1513.
PMID: 32606137
The cell of origin of oncogenic transformation is a determinant of therapeutic sensitivity, but the mechanisms governing cell-of-origin-driven differences in therapeutic response have not been delineated. Leukemias initiating in hematopoietic...
5.
Williams R, Shah J, Tian H, Chen X, Geissmann F, Jaimes E, et al.
Hypertension
. 2017 Nov;
71(1):87-94.
PMID: 29133360
Direct targeting to the kidneys is a promising strategy to improve drug therapeutic index for the treatment of kidney diseases. We sought to investigate the renal selectivity and safety of...
6.
Fitamant J, Kottakis F, Benhamouche S, Tian H, Chuvin N, Parachoniak C, et al.
Cell Rep
. 2015 Mar;
10(10):1692-1707.
PMID: 25772357
Defective Hippo/YAP signaling in the liver results in tissue overgrowth and development of hepatocellular carcinoma (HCC). Here, we uncover mechanisms of YAP-mediated hepatocyte reprogramming and HCC pathogenesis. YAP functions as...