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Sami El-Hilali

Explore the profile of Sami El-Hilali including associated specialties, affiliations and a list of published articles. Areas
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Articles 2
Citations 65
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Recent Articles
1.
Brison O, Gnan S, Azar D, Koundrioukoff S, Melendez-Garcia R, Kim S, et al.
Nat Struct Mol Biol . 2023 Apr; 30(4):539-550. PMID: 37024657
Genome integrity requires replication to be completed before chromosome segregation. The DNA-replication checkpoint (DRC) contributes to this coordination by inhibiting CDK1, which delays mitotic onset. Under-replication of common fragile sites...
2.
Brison O, El-Hilali S, Azar D, Koundrioukoff S, Schmidt M, Nahse V, et al.
Nat Commun . 2019 Dec; 10(1):5693. PMID: 31836700
Common fragile sites (CFSs) are chromosome regions prone to breakage upon replication stress known to drive chromosome rearrangements during oncogenesis. Most CFSs nest in large expressed genes, suggesting that transcription...