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Sameet Mehta

Explore the profile of Sameet Mehta including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 1238
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Recent Articles
1.
Mostaghimi D, Mehta S, Yoon J, Kosana P, Marra C, Corley M, et al.
J Infect Dis . 2024 Oct; PMID: 39356164
Epigenetic changes within immune cells may contribute to neuroinflammation during bacterial infection, but its role in neurosyphilis pathogenesis and response has not yet been established. We longitudinally analyzed DNA methylation...
2.
Islam R, White J, Arefin T, Mehta S, Liu X, Polis B, et al.
Biol Sex Differ . 2024 May; 15(1):39. PMID: 38715106
Background: Early life adversity impairs hippocampal development and function across diverse species. While initial evidence indicated potential variations between males and females, further research is required to validate these observations...
3.
Lee H, Zhao Y, Fleming I, Mehta S, Wang X, Vander Wyk B, et al.
iScience . 2023 Dec; 26(12):108387. PMID: 38047068
Infection with West Nile virus (WNV) drives a wide range of responses, from asymptomatic to flu-like symptoms/fever or severe cases of encephalitis and death. To identify cellular and molecular signatures...
4.
Korde A, Haslip M, Pednekar P, Khan A, Chioccioli M, Mehta S, et al.
JCI Insight . 2023 Sep; 8(18). PMID: 37737266
Acute lung injury (ALI) and its most severe form, acute respiratory distress syndrome (ARDS), cause severe endothelial dysfunction in the lung, and vascular endothelial growth factor (VEGF) is elevated in...
5.
Gunawardhana K, Hong L, Rugira T, Uebbing S, Kucharczak J, Mehta S, et al.
J Clin Invest . 2023 Jan; 133(4). PMID: 36602864
Genetic variants in the third intron of the PRDM6 gene have been associated with BP traits in multiple GWAS. By combining fine mapping, massively parallel reporter assays, and gene editing,...
6.
Zhang H, Li B, Huang Q, Lopez-Giraldez F, Tanaka Y, Lin Q, et al.
Nat Commun . 2022 Dec; 13(1):7637. PMID: 36496409
Although mitochondrial activity is critical for angiogenesis, its mechanism is not entirely clear. Here we show that mice with endothelial deficiency of any one of the three nuclear genes encoding...
7.
Boddupalli C, Nair S, Belinsky G, Gans J, Teeple E, Nguyen T, et al.
Elife . 2022 Aug; 11. PMID: 35972072
Background: Neuronopathic Gaucher disease (nGD) is a rare neurodegenerative disorder caused by biallelic mutations in and buildup of glycosphingolipids in lysosomes. Neuronal injury and cell death are prominent pathological features;...
8.
Tang X, Cao Y, Arora G, Hwang J, Sajid A, Brown C, et al.
Elife . 2022 Feb; 11. PMID: 35179491
No abstract available.
9.
Hong L, Li N, Gasque V, Mehta S, Ye L, Wu Y, et al.
JCI Insight . 2022 Feb; 7(4). PMID: 35108221
The molecular mechanisms that drive the acquisition of distinct neural crest cell (NCC) fates is still poorly understood. Here, we identified Prdm6 as an epigenetic modifier that temporally and spatially...
10.
Tang X, Cao Y, Arora G, Hwang J, Sajid A, Brown C, et al.
Elife . 2021 Nov; 10. PMID: 34783654
Adiponectin-mediated pathways contribute to mammalian homeostasis; however, little is known about adiponectin and adiponectin receptor signaling in arthropods. In this study, we demonstrate that ticks have an adiponectin receptor-like protein...