Sameer Chavan
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Explore the profile of Sameer Chavan including associated specialties, affiliations and a list of published articles.
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25
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787
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Recent Articles
1.
Slack S, Esquinca E, Arehart C, Boorgula M, Szczesny B, Romero A, et al.
medRxiv
. 2025 Feb;
PMID: 39974046
Background: Genetic control of gene expression in asthma-related tissues is not well-characterized, particularly for African-ancestry populations, limiting advancement in our understanding of the increased prevalence and severity of asthma in...
2.
Szczesny B, Boorgula M, Chavan S, Campbell M, Johnson R, Kammers K, et al.
Nat Commun
. 2024 May;
15(1):4546.
PMID: 38806494
Asthma has striking disparities across ancestral groups, but the molecular underpinning of these differences is poorly understood and minimally studied. A goal of the Consortium on Asthma among African-ancestry Populations...
3.
Wiley L, Shortt J, Roberts E, Lowery J, Kudron E, Lin M, et al.
Am J Hum Genet
. 2024 Jan;
111(1):11-23.
PMID: 38181729
Precision medicine initiatives across the globe have led to a revolution of repositories linking large-scale genomic data with electronic health records, enabling genomic analyses across the entire phenome. Many of...
4.
Pozdeyev N, Dighe M, Barrio M, Raeburn C, Smith H, Fisher M, et al.
J Clin Endocrinol Metab
. 2023 Sep;
109(2):402-412.
PMID: 37683082
Context: Thyroid nodule ultrasound-based risk stratification schemas rely on the presence of high-risk sonographic features. However, some malignant thyroid nodules have benign appearance on thyroid ultrasound. New methods for thyroid...
5.
Zhang X, Brody J, Graff M, Highland H, Chami N, Xu H, et al.
medRxiv
. 2023 Sep;
PMID: 37662265
Obesity is a major public health crisis associated with high mortality rates. Previous genome-wide association studies (GWAS) investigating body mass index (BMI) have largely relied on imputed data from European...
6.
Zhou W, Kanai M, Wu K, Rasheed H, Tsuo K, Hirbo J, et al.
Cell Genom
. 2023 Feb;
2(10):100192.
PMID: 36777996
Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry....
7.
Chen F, Wang X, Jang S, Quach B, Weissenkampen J, Khunsriraksakul C, et al.
Nat Genet
. 2023 Jan;
55(2):291-300.
PMID: 36702996
Most transcriptome-wide association studies (TWASs) so far focus on European ancestry and lack diversity. To overcome this limitation, we aggregated genome-wide association study (GWAS) summary statistics, whole-genome sequences and expression...
8.
Young K, Fisher V, Deng X, Brody J, Graff M, Lim E, et al.
HGG Adv
. 2022 Dec;
4(1):100163.
PMID: 36568030
Anthropometric traits, measuring body size and shape, are highly heritable and significant clinical risk factors for cardiometabolic disorders. These traits have been extensively studied in genome-wide association studies (GWASs), with...
9.
Saunders G, Wang X, Chen F, Jang S, Liu M, Wang C, et al.
Nature
. 2022 Dec;
612(7941):720-724.
PMID: 36477530
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide deaths, respectively, due largely to broad increased risk for disease and injury. These substances are used...
10.
Jang S, Evans L, Fialkowski A, Arnett D, Ashley-Koch A, Barnes K, et al.
Nat Hum Behav
. 2022 Aug;
6(11):1577-1586.
PMID: 35927319
Common genetic variants explain less variation in complex phenotypes than inferred from family-based studies, and there is a debate on the source of this 'missing heritability'. We investigated the contribution...