Rasika A Mathias
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Explore the profile of Rasika A Mathias including associated specialties, affiliations and a list of published articles.
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207
Citations
7665
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Recent Articles
1.
Slack S, Esquinca E, Arehart C, Boorgula M, Szczesny B, Romero A, et al.
medRxiv
. 2025 Feb;
PMID: 39974046
Background: Genetic control of gene expression in asthma-related tissues is not well-characterized, particularly for African-ancestry populations, limiting advancement in our understanding of the increased prevalence and severity of asthma in...
2.
Iyer K, Clarke S, Guarischi-Sousa R, Gjoni K, Heath A, Young E, et al.
J Am Heart Assoc
. 2025 Feb;
14(4):e036499.
PMID: 39950338
Background: Genome-wide association studies have identified several hundred susceptibility single nucleotide variants for coronary artery disease (CAD). Despite single nucleotide variant-based genome-wide association studies improving our understanding of the genetics...
3.
Li X, Chen H, Selvaraj M, Van Buren E, Zhou H, Wang Y, et al.
Nat Comput Sci
. 2025 Feb;
5(2):125-143.
PMID: 39920506
Large-scale whole-genome sequencing (WGS) studies have improved our understanding of the contributions of coding and noncoding rare variants to complex human traits. Leveraging association effect sizes across multiple traits in...
4.
Jakubek Y, Ma X, Stilp A, Yu F, Bacon J, Wong J, et al.
Am J Hum Genet
. 2025 Jan;
112(2):276-290.
PMID: 39809269
Mosaic loss of Y (mLOY) is the most common somatic chromosomal alteration detected in human blood. The presence of mLOY is associated with altered blood cell counts and increased risk...
5.
Liu F, Schrack J, Walker K, Walston J, Mathias R, Griswold M, et al.
medRxiv
. 2025 Jan;
PMID: 39802786
Clinical trials have shown favorable effects of exercise on frailty, supporting physical activity (PA) as a treatment and prevention strategy. Proteomics studies suggest that PA alters levels of many proteins,...
6.
Abers M, Mathias R
J Allergy Clin Immunol
. 2025 Jan;
155(3):813-814.
PMID: 39761797
No abstract available.
7.
De La Vega F, Barnes K, Bland H, Edwards T, Fox K, Ioannidis A, et al.
Pac Symp Biocomput
. 2024 Dec;
30:247-250.
PMID: 39670374
The following sections are included: Overview, Advancing multi-ancestry genetic research, Integrating social determinants of health to enhance genetic risk models, Methods to detect and mitigate disparities, Addressing Disparities in Adverse...
8.
Huffman J, Nicholas J, Hahn J, Heath A, Raffield L, Yanek L, et al.
Blood
. 2024 Sep;
144(21):2248-2265.
PMID: 39226462
Genetic studies have identified numerous regions associated with plasma fibrinogen levels in Europeans, yet missing heritability and limited inclusion of non-Europeans necessitates further studies with improved power and sensitivity. Compared...
9.
Liu F, Schrack J, Walston J, Mathias R, Windham B, Grams M, et al.
Geroscience
. 2024 Jun;
46(5):5247-5265.
PMID: 38856871
Physical frailty is a syndrome that typically manifests in later life, although the pathogenic process causing physical frailty likely begins decades earlier. To date, few studies have examined the biological...
10.
Mack T, Raddatz M, Pershad Y, Nachun D, Taylor K, Guo X, et al.
Nat Aging
. 2024 Jun;
4(8):1043-1052.
PMID: 38834882
Clonal hematopoiesis of indeterminate potential (CHIP), whereby somatic mutations in hematopoietic stem cells confer a selective advantage and drive clonal expansion, not only correlates with age but also confers increased...