Samantha Gadd
Overview
Explore the profile of Samantha Gadd including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
743
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0
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Recent Articles
1.
Lang A, Gadd S, Gunderman L, Lippner E, Devonshire A, Schipma M, et al.
Clin Exp Allergy
. 2024 Oct;
55(1):100-103.
PMID: 39415357
No abstract available.
2.
Watanabe J, Clutter M, Gullette M, Sasaki T, Uchida E, Kaur S, et al.
J Clin Invest
. 2024 May;
134(13).
PMID: 38771655
Diffuse midline glioma (DMG) H3K27-altered is one of the most malignant childhood cancers. Radiation therapy remains the only effective treatment yet provides a 5-year survival rate of only 1%. Several...
3.
Perotti D, Williams R, Wegert J, Brzezinski J, Maschietto M, Ciceri S, et al.
Nat Rev Urol
. 2023 Oct;
21(3):158-180.
PMID: 37848532
The modern study of Wilms tumour was prompted nearly 50 years ago, when Alfred Knudson proposed the 'two-hit' model of tumour development. Since then, the efforts of researchers worldwide have...
4.
Modi A, Lopez G, Conkrite K, Su C, Leung T, Ramanan S, et al.
Cancer Res
. 2023 Aug;
83(20):3462-3477.
PMID: 37584517
Significance: Comprehensive characterization of lncRNAs in pediatric cancer leads to the identification of highly expressed lncRNAs across childhood cancers, annotation of lncRNAs showing histotype-specific elevated expression, and prediction of lncRNA...
5.
Gadd S, Huff V, Skol A, Renfro L, Fernandez C, Mullen E, et al.
Cell Rep Med
. 2022 May;
3(6):100644.
PMID: 35617957
Over the last decade, sequencing of primary tumors has clarified the genetic underpinnings of Wilms tumor but has not affected therapy, outcome, or toxicity. We now sharpen our focus on...
6.
Tomita Y, Shimazu Y, Somasundaram A, Tanaka Y, Takata N, Ishi Y, et al.
Glia
. 2022 May;
70(9):1681-1698.
PMID: 35524725
Diffuse midline glioma (DMG) is a type of lethal brain tumor that develops mainly in children. The majority of DMG harbor the K27M mutation in histone H3. Oligodendrocyte progenitor cells...
7.
Dhar S, Gadd S, Patel P, Vaynshteyn J, Raju G, Hashizume R, et al.
Acta Neuropathol Commun
. 2022 Apr;
10(1):47.
PMID: 35395831
Pediatric high-grade gliomas, specifically diffuse midline gliomas, account for only 20% of clinical cases but are 100% fatal. A majority of the DMG cases are characterized by the signature K27M...
8.
Ortiz M, Ahmed S, Burns M, Henssen A, Hollmann T, MacArthur I, et al.
JCI Insight
. 2019 Aug;
4(15).
PMID: 31391345
Wilms' tumor is the most common type of childhood kidney cancer. To improve risk stratification and identify novel therapeutic targets for patients with Wilms' tumor, we used high-resolution mass spectrometry...
9.
Hoeman C, Cordero F, Hu G, Misuraca K, Romero M, Cardona H, et al.
Nat Commun
. 2019 Mar;
10(1):1023.
PMID: 30833574
Diffuse intrinsic pontine glioma (DIPG) is an incurable pediatric brain tumor, with approximately 25% of DIPGs harboring activating ACVR1 mutations that commonly co-associate with H3.1K27M mutations. Here we show that...
10.
Armstrong A, Gadd S, Huff V, Gerhard D, Dome J, Perlman E
PLoS One
. 2018 Dec;
13(12):e0208936.
PMID: 30543698
This study explores the genomic alterations that contribute to the formation of a unique subset of low-risk, epithelial differentiated, favorable histology Wilms tumors (WT), tumors that have been characterized by...