Daniela S Gerhard
Overview
Explore the profile of Daniela S Gerhard including associated specialties, affiliations and a list of published articles.
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76
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12965
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Recent Articles
1.
Kim J, Vaksman Z, Egolf L, Kaufman R, Evans J, Conkrite K, et al.
J Natl Cancer Inst
. 2023 Sep;
116(1):149-159.
PMID: 37688579
Background: Neuroblastoma is an embryonal cancer of the developing sympathetic nervous system. The genetic contribution of rare pathogenic or likely pathogenic germline variants in patients without a family history remains...
2.
Kim J, Vaksman Z, Egolf L, Kaufman R, Evans J, Conkrite K, et al.
medRxiv
. 2023 Feb;
PMID: 36747619
Importance: Neuroblastoma accounts for 12% of childhood cancer deaths. The genetic contribution of rare pathogenic germline variation in patients without a family history remains unclear. Objective: To define the prevalence,...
3.
Thomas N, Dreval K, Gerhard D, Hilton L, Abramson J, Ambinder R, et al.
Blood
. 2022 Oct;
141(8):904-916.
PMID: 36201743
Burkitt lymphoma (BL) accounts for most pediatric non-Hodgkin lymphomas, being less common but significantly more lethal when diagnosed in adults. Much of the knowledge of the genetics of BL thus...
4.
Brady S, Roberts K, Gu Z, Shi L, Pounds S, Pei D, et al.
Nat Genet
. 2022 Sep;
54(9):1376-1389.
PMID: 36050548
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL, we find that, despite a generally low...
5.
Douglass Jr E, Allaway R, Szalai B, Wang W, Tian T, Fernandez-Torras A, et al.
Cell Rep Med
. 2022 Feb;
3(1):100492.
PMID: 35106508
The Columbia Cancer Target Discovery and Development (CTD2) Center is developing PANACEA, a resource comprising dose-responses and RNA sequencing (RNA-seq) profiles of 25 cell lines perturbed with ∼400 clinical oncology...
6.
Heath A, Ferretti V, Agrawal S, An M, Angelakos J, Arya R, et al.
Nat Genet
. 2021 May;
53(6):935.
PMID: 34007079
No abstract available.
7.
Hahn W, Bader J, Braun T, Califano A, Clemons P, Druker B, et al.
Cell
. 2021 Mar;
184(5):1142-1155.
PMID: 33667368
The characterization of cancer genomes has provided insight into somatically altered genes across tumors, transformed our understanding of cancer biology, and enabled tailoring of therapeutic strategies. However, the function of...
8.
Heath A, Ferretti V, Agrawal S, An M, Angelakos J, Arya R, et al.
Nat Genet
. 2021 Feb;
53(3):257-262.
PMID: 33619384
No abstract available.
9.
Whalley J, Buchhalter I, Rheinbay E, Raine K, Stobbe M, Kleinheinz K, et al.
Nat Commun
. 2020 Oct;
11(1):5040.
PMID: 33028839
Bringing together cancer genomes from different projects increases power and allows the investigation of pan-cancer, molecular mechanisms. However, working with whole genomes sequenced over several years in different sequencing centres...
10.
Lopez G, Conkrite K, Doepner M, Rathi K, Modi A, Vaksman Z, et al.
Genome Res
. 2020 Aug;
30(9):1228-1242.
PMID: 32796005
Neuroblastoma is a malignancy of the developing sympathetic nervous system that accounts for 12% of childhood cancer deaths. Like many childhood cancers, neuroblastoma shows a relative paucity of somatic single-nucleotide...