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Sam Li

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Articles 27
Citations 1338
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Recent Articles
1.
Li S, Fernandez J, Ruehle M, Howard-Till R, Fabritius A, Pearson C, et al.
EMBO J . 2025 Feb; PMID: 39994484
The cilium is a microtubule-based eukaryotic organelle critical for many cellular functions. Its assembly initiates at a basal body and continues as an axoneme that projects out of the cell...
2.
Howard-Till R, Li S, Pallabi Kar U, Fuentes C, Fabritius A, Winey M
Mol Biol Cell . 2025 Feb; 36(4):br13. PMID: 39937672
The lumens of the highly stable microtubules that make up the core of basal bodies, cilia, and flagella are coated with a network of proteins known as MIPs, or microtubule...
3.
Kaveeshwar S, Hasan S, Polsky D, OHara N, Honig E, Li S, et al.
J Orthop . 2024 Sep; 60:19-24. PMID: 39345677
Background: We aimed to determine if Area Deprivation Index (ADI) is associated with self-reported metrics socioeconomic status (SES), and to assess the relationship between ADI and preoperative score on common...
4.
Li S, Fernandez J, Ruehle M, Howard-Till R, Fabritius A, Pearson C, et al.
bioRxiv . 2024 Sep; PMID: 39314311
The cilium is a microtubule-based organelle critical for many cellular functions. Its assembly initiates at a basal body and continues as an axoneme that projects out of the cell to...
5.
Ruehle M, Li S, Agard D, Pearson C
J Cell Biol . 2024 May; 223(8). PMID: 38743010
Basal bodies (BBs) are conserved eukaryotic structures that organize cilia. They are comprised of nine, cylindrically arranged, triplet microtubules (TMTs) connected to each other by inter-TMT linkages which stabilize the...
6.
Ruehle M, Li S, Agard D, Pearson C
bioRxiv . 2023 Nov; PMID: 38014135
Basal bodies (BBs) are conserved eukaryotic structures that organize motile and primary cilia. The BB is comprised of nine, cylindrically arranged, triplet microtubules (TMTs) that are connected to each other...
7.
Courelli A, Sharma A, Madlensky L, Choi Y, Li S, Sarno S, et al.
Ann Surg Oncol . 2022 Jul; 29(12):7542-7548. PMID: 35849291
Purpose: Gastrointestinal stromal tumor (GIST) is associated with increased risk of additional cancers. In this study, synchronous GIST, and peritoneal mesothelioma (PM) were characterized to evaluate the relationship between these...
8.
Li S, Fernandez J, Fabritius A, Agard D, Winey M
Life Sci Alliance . 2021 Dec; 5(3). PMID: 34969817
Doublet microtubules (DMTs) provide a scaffold for axoneme assembly in motile cilia. Aside from α/β tubulins, the DMT comprises a large number of non-tubulin proteins in the luminal wall of...
9.
Yebra M, Bhargava S, Kumar A, Burgoyne A, Tang C, Yoon H, et al.
Clin Cancer Res . 2021 Aug; 28(1):187-200. PMID: 34426440
Purpose: Gastrointestinal stromal tumor (GIST) is the most common sarcoma of the gastrointestinal tract, with mutant succinate dehydrogenase () subunits (A-D) comprising less than 7.5% (i.e., 150-200/year) of new cases...
10.
Fernandez J, Li S
J Struct Biol . 2021 Aug; 213(4):107778. PMID: 34416376
TomoAlign is a software package that integrates tools to mitigate two important resolution limiting factors in cryoET, namely the beam-induced sample motion and the contrast transfer function (CTF) of the...