Sam Chen
Overview
Explore the profile of Sam Chen including associated specialties, affiliations and a list of published articles.
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33
Citations
1898
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Recent Articles
1.
Hogan J, Liu C, Zhang H, Salisu A, Villamanca D, Zheng J, et al.
ACS Nano
. 2025 Jan;
19(1):546-556.
PMID: 39746733
Fullerenes, with well-defined molecular structures and high scalability, hold promise as fundamental building blocks for creating a variety of carbon materials. The fabrication and transfer of large-area films with precisely...
2.
Flexible fluorinated graphite foils with high contents of the (CF) phase for slow neutron reflectors
Henry K, Colin M, Chambery G, Vigolo B, Cahen S, Herold C, et al.
Dalton Trans
. 2024 May;
53(22):9473-9481.
PMID: 38767605
In order to prepare self-standing and flexible slow neutron reflectors made of graphite fluoride (GF) with high contents of (CF) structural phase, graphite foils of different thicknesses were used as...
3.
Jakubek Z, Chen S, Zaifman J, Tam Y, Zou S
Langmuir
. 2023 Feb;
39(7):2509-2519.
PMID: 36748988
With recent advances and anticipated proliferation of lipid nanoparticle (LNP)-delivered vaccines and therapeutics, there is a need for the availability of internationally recognized reference materials of LNP systems. Accordingly, we...
4.
Alhussan A, Jackson N, Eaton S, Dos Santos N, Barta I, Zaifman J, et al.
Cancers (Basel)
. 2022 Dec;
14(24).
PMID: 36551622
Current chemoradiation therapy suffers from normal tissue toxicity. Thus, we are proposing incorporating gold nanoparticles (GNPs) and docetaxel (DTX), as they have shown very promising synergetic radiosensitization effects. Here, we...
5.
Syama K, Jakubek Z, Chen S, Zaifman J, Tam Y, Zou S
Sci Rep
. 2022 Oct;
12(1):18071.
PMID: 36302886
Lipid based nanocarriers are one of the most effective drug delivery systems that is evident from the recent COVID-19 mRNA vaccines. The main objective of this study was to evaluate...
6.
van der Meel R, Chen S, Zaifman J, Kulkarni J, Zhang X, Tam Y, et al.
Small
. 2021 Aug;
17(37):e2103025.
PMID: 34337865
Successfully employing small interfering RNA (siRNA) therapeutics requires the use of nanotechnology for efficient intracellular delivery. Lipid nanoparticles (LNPs) have enabled the approval of various nucleic acid therapeutics. A major...
7.
Kulkarni J, Witzigmann D, Thomson S, Chen S, Leavitt B, Cullis P, et al.
Nat Nanotechnol
. 2021 Jul;
16(7):841.
PMID: 34194013
No abstract available.
8.
Kulkarni J, Chen S, Tam Y
Langmuir
. 2021 Jun;
37(24):7312-7319.
PMID: 34101472
Lipid-based formulations have been developed to improve stability profiles, tolerability, and toxicity profiles of small molecule drugs. However, manufacture of such formulations involving lipophilic compounds can be labor-intensive and difficult...
9.
Kulkarni J, Witzigmann D, Thomson S, Chen S, Leavitt B, Cullis P, et al.
Nat Nanotechnol
. 2021 Jun;
16(6):630-643.
PMID: 34059811
The increasing number of approved nucleic acid therapeutics demonstrates the potential to treat diseases by targeting their genetic blueprints in vivo. Conventional treatments generally induce therapeutic effects that are transient...
10.
Terada T, Kulkarni J, Huynh A, Chen S, van der Meel R, Tam Y, et al.
Langmuir
. 2021 Jan;
37(3):1120-1128.
PMID: 33439022
Lipid nanoparticles (LNPs) containing short-interfering RNA (LNP-siRNA systems) are a promising approach for silencing disease-causing genes in hepatocytes following intravenous administration. LNP-siRNA systems are generated by rapid mixing of lipids...