Sai Prasad N Iyer
Overview
Explore the profile of Sai Prasad N Iyer including associated specialties, affiliations and a list of published articles.
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17
Citations
1482
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Recent Articles
11.
Garcia-Calvo M, Lisnock J, Bull H, Hawes B, Burnett D, Braun M, et al.
Proc Natl Acad Sci U S A
. 2005 Jun;
102(23):8132-7.
PMID: 15928087
Ezetimibe is a potent inhibitor of cholesterol absorption that has been approved for the treatment of hypercholesterolemia, but its molecular target has been elusive. Using a genetic approach, we recently...
12.
Iyer S, Yao X, Crona J, Hoos L, Tetzloff G, Davis Jr H, et al.
Biochim Biophys Acta
. 2005 Mar;
1722(3):282-92.
PMID: 15777641
The exact mechanistic pathway of cholesterol absorption in the jejunum of the small intestines is a poorly understood process. Recently, a relatively novel gene, Niemann-Pick C1 Like 1 (NPC1L1), was...
13.
Davis Jr H, Zhu L, Hoos L, Tetzloff G, Maguire M, Liu J, et al.
J Biol Chem
. 2004 Jun;
279(32):33586-92.
PMID: 15173162
Niemann-Pick C1 Like 1 (NPC1L1) is a protein localized in jejunal enterocytes that is critical for intestinal cholesterol absorption. The uptake of intestinal phytosterols and cholesterol into absorptive enterocytes in...
14.
Altmann S, Davis Jr H, Zhu L, Yao X, Hoos L, Tetzloff G, et al.
Science
. 2004 Feb;
303(5661):1201-4.
PMID: 14976318
Dietary cholesterol consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, a risk factor for coronary heart disease. The molecular mechanism of sterol uptake from the lumen of the...
15.
Iyer S, Hart G
J Biol Chem
. 2003 May;
278(27):24608-16.
PMID: 12724313
The abundant and dynamic post-translational modification of nuclear and cytosolic proteins by beta-O-linked N-acetylglucosamine (O-GlcNAc) is catalyzed by O-GlcNAc-transferase (OGT). Recently, we reported the identification of a novel family of...
16.
17.
Iyer S, Akimoto Y, Hart G
J Biol Chem
. 2002 Nov;
278(7):5399-409.
PMID: 12435728
The abundant and dynamic post-translational modification of nuclear and cytosolic proteins by beta-O-linked N-acetylglucosamine (O-GlcNAc) is catalyzed by O-GlcNAc transferase (OGT). Here we used the yeast two-hybrid approach to identify...