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Sadie X Novak

Explore the profile of Sadie X Novak including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 19
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Recent Articles
1.
Pierce M, Ji J, Novak S, Sieburg M, Nangia S, Nangia S, et al.
J Chem Inf Model . 2023 Nov; 63(22):7159-7170. PMID: 37939203
Membrane proteins are difficult to isolate and purify due to their dependence on the surrounding lipid membrane for structural stability. Detergents are often used to solubilize these proteins, with this...
2.
Campana M, Davis T, Novak S, Cleverdon E, Bates M, Krishnan N, et al.
ACS Chem Biol . 2023 Jul; 18(8):1880-1890. PMID: 37494676
Ghrelin acyltransferase (GOAT) plays a central role in the maturation and activation of the peptide hormone ghrelin, which performs a wide range of endocrinological signaling roles. Using a tight-binding fluorescent...
3.
Schey G, Buttery P, Hildebrandt E, Novak S, Schmidt W, Hougland J, et al.
Int J Mol Sci . 2021 Nov; 22(21). PMID: 34769472
Protein farnesylation is a post-translational modification where a 15-carbon farnesyl isoprenoid is appended to the C-terminal end of a protein by farnesyltransferase (FTase). This modification typically causes proteins to associate...
4.
Davis T, Pierce M, Novak S, Hougland J
Open Biol . 2021 Jul; 11(7):210080. PMID: 34315274
The acylated peptide hormone ghrelin impacts a wide range of physiological processes but is most well known for controlling hunger and metabolic regulation. Ghrelin requires a unique posttranslational modification, serine...