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Mariah R Pierce

Explore the profile of Mariah R Pierce including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Pierce M, Ji J, Novak S, Sieburg M, Nangia S, Nangia S, et al.
J Chem Inf Model . 2023 Nov; 63(22):7159-7170. PMID: 37939203
Membrane proteins are difficult to isolate and purify due to their dependence on the surrounding lipid membrane for structural stability. Detergents are often used to solubilize these proteins, with this...
2.
Campana M, Davis T, Novak S, Cleverdon E, Bates M, Krishnan N, et al.
ACS Chem Biol . 2023 Jul; 18(8):1880-1890. PMID: 37494676
Ghrelin acyltransferase (GOAT) plays a central role in the maturation and activation of the peptide hormone ghrelin, which performs a wide range of endocrinological signaling roles. Using a tight-binding fluorescent...
3.
Pierce M, Hougland J
Front Physiol . 2023 May; 14:1167873. PMID: 37250116
Acylation modifications play a central role in biological and physiological processes. Across a range of biomolecules from phospholipids to triglycerides to proteins, introduction of a hydrophobic acyl chain can dramatically...
4.
Davis T, Pierce M, Novak S, Hougland J
Open Biol . 2021 Jul; 11(7):210080. PMID: 34315274
The acylated peptide hormone ghrelin impacts a wide range of physiological processes but is most well known for controlling hunger and metabolic regulation. Ghrelin requires a unique posttranslational modification, serine...