Sadasivan Vidyasagar
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Explore the profile of Sadasivan Vidyasagar including associated specialties, affiliations and a list of published articles.
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46
Citations
658
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Recent Articles
11.
Gupta R, Yin L, Grosche A, Lin S, Xu X, Guo J, et al.
J Nutr
. 2020 Mar;
150(5):1100-1108.
PMID: 32133527
Background: Radiotherapy inadvertently affects gastrointestinal (GI) epithelial cells, causing intestinal barrier disruption and increased permeability. Objective: We examined the effect of amino acid-based oral rehydration solution (AA-ORS) on radiation-induced changes...
12.
Wang X, Zhang M, Flores S, Woloshun R, Yang C, Yin L, et al.
Mol Ther
. 2019 Feb;
27(3):493-506.
PMID: 30713087
Nanoparticles (NPs) have been utilized to deliver drugs to the intestinal epithelium in vivo. Moreover, NPs derived from edible plants are less toxic than synthetic NPs. Here, we utilized ginger...
13.
Wang X, Flores S, Ha J, Doguer C, Woloshun R, Xiang P, et al.
J Nutr
. 2018 Aug;
148(8):1244-1252.
PMID: 30137476
Background: Divalent metal-ion transporter 1 (DMT1) may transport copper, but studies to date on this topic have been equivocal. Previously, an ex vivo experiment showed that intestinal copper transport was...
14.
Sollanek K, Tsurumoto M, Vidyasagar S, Kenefick R, Cheuvront S
Am J Clin Nutr
. 2018 Apr;
107(4):544-549.
PMID: 29635499
Background: The beverage hydration index (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric, and the impact of body mass,...
15.
Cheuvront S, Kenefick R, Charkoudian N, Mitchell K, Luippold A, Bradbury K, et al.
JPEN J Parenter Enteral Nutr
. 2018 Jan;
42(7):1185-1193.
PMID: 29377181
Background: The efficacy of different commercial beverage compositions for meeting oral rehydration therapy (ORT) goals in the treatment of acute dehydration in healthy humans has not been systematically tested. The...
16.
Zhang S, Yang S, Zhang Z, Zhang A, Zhang M, Yin L, et al.
Int J Radiat Biol
. 2017 Oct;
93(12):1334-1342.
PMID: 29063809
Purpose: To investigate the late effects of thoracic region irradiation (TRI) on mouse body weight. Materials And Methods: Female C57BL/6 mice were divided into nonirradiated, 5 Gy total body irradiation,...
17.
Yin L, Vaught L, Okunieff P, Casey-Sawicki K, Vidyasagar S
Adv Exp Med Biol
. 2017 Jul;
977:59-65.
PMID: 28685428
Nausea and diarrhea are common yet inconsistent side effects of abdominal and pelvic irradiation. Their frequency, chronicity, and severity vary greatly, and the reasons for inter-subject variability are unknown. We...
18.
Yin L, Menon R, Gupta R, Vaught L, Okunieff P, Vidyasagar S
Pflugers Arch
. 2017 May;
469(9):1093-1105.
PMID: 28488023
Rotavirus causes severe diarrhea in small children and is typically treated using glucose-containing oral rehydration solutions; however, glucose may have a detrimental impact on these patients, because it increases chloride...
19.
Yin L, Gupta R, Vaught L, Grosche A, Okunieff P, Vidyasagar S
Sci Rep
. 2016 Nov;
6:37220.
PMID: 27876791
Destruction of clonogenic cells in the crypt following irradiation are thought to cause altered gastrointestinal function. Previously, we found that an amino acid-based oral rehydration solution (AA-ORS) improved gastrointestinal function...
20.
Liu C, Zhang M, Zhang Z, Zhang S, Yang S, Zhang A, et al.
Bioorg Med Chem
. 2016 Jul;
24(18):4263-4271.
PMID: 27448774
In an effort to develop new drug candidates with enhanced anticancer activity, our team synthesized and assessed the cytotoxicity of a series of novel xanthone derivatives with two longer 3,6-disubstituted...